DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and IGSF9B

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001264214.1	Gene:	IGSF9B / 22997	HGNCID:	32326	Length:	1437	Species:	Homo sapiens

Alignment Length:	204	Identity:	49/204 - (24%)
Similarity:	78/204 - (38%)	Gaps:	50/204 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 ISTQLSSSVYLHCRV-NDLQGK----TVSWMRRRGDDLTLITFGQHTYSGDSRYSLEFEEPNDWK 143
            ::.:...||.|.|.| :.:.|:    .|.|.:........|.||.:....|..|:......:...
Human    33 VTARAGESVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEYAGRASLHDKAS 97

  Fly   144 LLIQFANERDEGPYECQVSSHPPLVL-----------LVYLTIIVPHVEILDERGSATPEKYYKA 197
            |.::.....|:|.|||:|     |:|           .|:|||..|      ...:.||.:|.:|
Human    98 LRLEQVRSEDQGWYECKV-----LMLDQQYDTFHNGSWVHLTINAP------PTFTETPPQYIEA 151

  Fly   198 --GSTIELQCVISKIPHPSSYITWRHGPRLL----NYDTSRGGISVKTDMLPGRALSRLYIANAN 256
              |.:|.:.|  :...:|...:||.....||    .|..|.|.::|               .:.:
Human   152 KEGGSITMTC--TAFGNPKPIVTWLKEGTLLGASGKYQVSDGSLTV---------------TSVS 199

  Fly   257 RQDTGNYTC 265
            |:|.|.|||
Human   200 REDRGAYTC 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	20/83 (24%)
		Ig	84..169	CDD:299845	21/89 (24%)
		IG_like	191..279	CDD:214653	21/81 (26%)
		Ig	201..274	CDD:143165	17/69 (25%)
IGSF9B	NP_001264214.1	IG_like	30..115	CDD:214653	19/81 (23%)
		Ig	41..115	CDD:143165	18/73 (25%)
		I-set	139..225	CDD:254352	22/87 (25%)
		IGc2	153..210	CDD:197706	18/73 (25%)
		I-set	229..321	CDD:254352
		Ig	235..321	CDD:299845
		IG_like	331..414	CDD:214653
		Ig	<353..414	CDD:299845
		IG_like	426..505	CDD:214653
		Ig	442..505	CDD:299845
		FN3	510..601	CDD:238020
		FN3	617..699	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	758..817
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	911..1081
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810