DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and igcm-2

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001362087.1	Gene:	igcm-2 / 180913	WormBaseID:	WBGene00020130	Length:	802	Species:	Caenorhabditis elegans

Alignment Length:	287	Identity:	67/287 - (23%)
Similarity:	100/287 - (34%)	Gaps:	66/287 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IIYSSLHHIGSGSTSTTLKRPRAGDP--FDTFPKNFWQEFSSPFTDTPEDEELEVTETTTHEPFP 73
            |.:|....|.|.|...||.....||.  :.....|.....:|..       ::..|:.|..:..|
Worm   157 ITWSRNEQIISTSPVLTLSNLEEGDKGLYTCLAVNIEGNSTSSI-------DVRFTKATILDLIP 214

  Fly    74 FFADPYTTLNISTQLSSSVYLHCRVNDLQGKTV--SWM-RRRGDDLTLITFGQHTYSGDSRYSLE 135
                    ||.:....|:|:.||..| .|...:  ||: .::....|.:....:..|||
Worm   215 --------LNKTVIEGSNVFWHCHAN-AQATAISYSWLFEKKPIKTTSLGLRSNIRSGD------ 264

  Fly   136 FEEPNDWKLLIQFANERDEGPYECQV--SSHPPLVLLVYLTIIVPHVEILDERGSATPEKYYKAG 198
                    |.:|...:.|.|.|.|:.  |:........||.:..|.    :...|..|.:...:|
Worm   265 --------LSLQDVRKSDSGWYTCEAKNSAGETTSSTAYLHVFYPP----EPLSSHQPVQTVASG 317

  Fly   199 STIELQCVISKIPHPSSYITWRHGPRLLNYDTSRGGISVKTDMLPGRALSRLYIANANRQDTGNY 263
            ....:.|.:...|.|:|| ||           |:.|     ..||.:|.|.:.|:.|...|.|.|
Worm   318 RNTTVSCDVIANPTPTSY-TW-----------SKNG-----HYLPTQASSHIIISYAKPGDGGIY 365

  Fly   264 TCMLGN-----EITETVVVHVLNGEEP 285
            .|...|     .|.||   |::..|.|
Worm   366 GCQADNIAGKGSIVET---HLIVAEPP 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	19/84 (23%)
		Ig	84..169	CDD:299845	19/89 (21%)
		IG_like	191..279	CDD:214653	25/92 (27%)
		Ig	201..274	CDD:143165	21/77 (27%)
igcm-2	NP_001362087.1	IG_like	23..101	CDD:214653
		Ig	124..200	CDD:386229	11/42 (26%)
		IG_like	214..298	CDD:214653	24/106 (23%)
		Ig_3	309..371	CDD:372822	21/78 (27%)
		Ig	389..467	CDD:386229	1/1 (100%)
		FN3	476..548	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900