DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and Ncam1

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_006510118.1	Gene:	Ncam1 / 17967	MGIID:	97281	Length:	1162	Species:	Mus musculus

Alignment Length:	238	Identity:	59/238 - (24%)
Similarity:	90/238 - (37%)	Gaps:	56/238 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 FFADPYTTLNI-------STQLSSSVYLHCRV-NDLQGKTVSWMRRRGDDLTLITFGQHTYSGDS 130
            ||.....:|.:       ...:..|.:..|:| .|.:.|.:||....|:.|:         ....
Mouse    12 FFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLS---------PNQQ 67

  Fly   131 RYSLEFEEPNDWKLLIQFANERDEGPYECQVSSHPPLVLLVYLTIIVPHVEILDERGSATPEKYY 195
            |.|:.:.:.:...|.|..||..|.|.|:|.|::...  .....|:.|...:.|..:.:.||:: :
Mouse    68 RISVVWNDDDSSTLTIYNANIDDAGIYKCVVTAEDG--TQSEATVNVKIFQKLMFKNAPTPQE-F 129

  Fly   196 KAGSTIELQC-VISKIPHPSSYITWRHGPRLL-------------NYDTSRGGISVKTD----ML 242
            |.|....:.| |:|.:| |:  |.|:|..|.:             ||...||  ..|||    ..
Mouse   130 KEGEDAVIVCDVVSSLP-PT--IIWKHKGRDVILKKDVRFIVLSNNYLQIRG--IKKTDEGTYRC 189

  Fly   243 PGRALSR--------LYIANA-----NRQDTGNYTCMLGNEIT 272
            .||.|:|        ..|.|.     .||...|.|..||..:|
Mouse   190 EGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVT 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	20/87 (23%)
		Ig	84..169	CDD:299845	20/92 (22%)
		IG_like	191..279	CDD:214653	32/113 (28%)
		Ig	201..274	CDD:143165	29/103 (28%)
Ncam1	XP_006510118.1	Ig1_NCAM-1	20..115	CDD:143273	23/105 (22%)
		IG	124..190	CDD:214652	20/71 (28%)
		Ig3_NCAM-1_like	211..308	CDD:143207	7/22 (32%)
		Ig_NCAM-1	307..413	CDD:143277
		Ig_3	417..494	CDD:372822
		FN3	509..606	CDD:238020
		fn3	649..731	CDD:365830
		PHA03247	<905..1140	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900