DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr14 and negr1

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_031755650.1	Gene:	negr1 / 100127726	XenbaseID:	XB-GENE-987949	Length:	388	Species:	Xenopus tropicalis

Alignment Length:	194	Identity:	50/194 - (25%)
Similarity:	82/194 - (42%)	Gaps:	34/194 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 NISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRYSLEFEEPNDWKLLIQ 147
            |:..:...:..|.|.:.:...|. :|:.|.    ::|..|...:|.|.|.|:......::.|.||
Frog    48 NLVVRQGETAMLRCFLEEGASKG-AWLNRS----SIIFAGGDKWSVDPRVSIATSSKQEYSLRIQ 107

  Fly   148 FANERDEGPYECQV-SSHPPLVLLVYLTIIVPHV--EILDERGSATPEKYYKAGSTIELQCVISK 209
            ..:..|:|||.|.| :.|.|..|.|:||:   ||  :|.|.....|..:    |:.:.|.|:.:.
Frog   108 KVDVSDDGPYTCSVQTEHSPRTLQVHLTV---HVSPKIYDISSDMTVNE----GTNVSLICLATG 165

  Fly   210 IPHPSSYITWRH-GPRLLNYDTSRGGISVKTDMLPGRALSRLYIANANRQDTGNYTCMLGNEIT 272
            .|.||  |:||| .|....:.:.:                .|.|....|...|:|.|...|:::
Frog   166 KPEPS--ISWRHISPSAKQFGSGQ----------------YLDIYGITRDQAGDYECSAENDVS 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	21/80 (26%)
		Ig	84..169	CDD:299845	22/85 (26%)
		IG_like	191..279	CDD:214653	18/83 (22%)
		Ig	201..274	CDD:143165	17/73 (23%)
negr1	XP_031755650.1	Ig	44..136	CDD:416386	26/92 (28%)
		FR1	44..62	CDD:409353	2/13 (15%)
		Ig strand A'	47..53	CDD:409353	1/4 (25%)
		Ig strand B	55..63	CDD:409353	2/7 (29%)
		CDR1	63..68	CDD:409353	0/4 (0%)
		FR2	69..75	CDD:409353	2/6 (33%)
		Ig strand C	69..74	CDD:409353	2/5 (40%)
		CDR2	76..87	CDD:409353	2/14 (14%)
		Ig strand C'	78..82	CDD:409353	1/3 (33%)
		Ig strand C'	84..87	CDD:409353	0/2 (0%)
		FR3	88..122	CDD:409353	11/33 (33%)
		Ig strand D	91..98	CDD:409353	2/6 (33%)
		Ig strand E	101..107	CDD:409353	1/5 (20%)
		Ig strand F	114..122	CDD:409353	4/7 (57%)
		CDR3	123..127	CDD:409353	1/3 (33%)
		Ig strand G	127..136	CDD:409353	4/8 (50%)
		FR4	129..136	CDD:409353	3/6 (50%)
		Ig_3	140..208	CDD:404760	20/89 (22%)
		Ig strand A'	146..151	CDD:409353	0/4 (0%)
		Ig strand B	157..164	CDD:409353	2/6 (33%)
		Ig strand C	170..175	CDD:409353	3/6 (50%)
		Ig strand C'	177..179	CDD:409353	0/1 (0%)
		Ig strand E	187..193	CDD:409353	2/21 (10%)
		Ig strand F	200..207	CDD:409353	3/6 (50%)
		Ig strand G	214..222	CDD:409353
		Ig_3	226..302	CDD:404760
		putative Ig strand A	226..232	CDD:409353
		Ig strand B	242..246	CDD:409353
		Ig strand C	255..259	CDD:409353
		Ig strand E	281..285	CDD:409353
		Ig strand F	295..300	CDD:409353
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000