DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bys and SPBC13G1.09

DIOPT Version :9

Sequence 1:	NP_511074.1	Gene:	bys / 31701	FlyBaseID:	FBgn0010292	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_596559.1	Gene:	SPBC13G1.09 / 2539887	PomBaseID:	SPBC13G1.09	Length:	449	Species:	Schizosaccharomyces pombe

Alignment Length:	453	Identity:	189/453 - (41%)
Similarity:	274/453 - (60%)	Gaps:	58/453 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KANVATIKNVNLEKQI---TEGRVAKNKNKDKVKLRAEESAN--IDARSSQKILAAAKLQQLELD 65
            ||....:.:..|.|.|   :|..|.:.|...:.|.:...:.|  :||::|:|||..|:.|:.|||
pombe     3 KAPKTKLHHAPLYKDIAESSESGVLRQKPSKQKKSKESNTGNGFLDAKTSKKILQLAREQKEELD 67

  Fly    66 EE--NFPSLVTVKKVNFSLNDGHVK------------------------------EDEEVNETDL 98
            ||  ..||     :::..:::||.|                              |:||..|
pombe    68 EEENGKPS-----QISAFISNGHQKDTLENPAIESSYEESEHARNVSDSESITSQEEEEYEE--- 124

  Fly    99 MADLDMDEDDVAAFERF--QQPAQEG----KRTLHLSKMIMQKIQEKEADI---HTKISDEGSLK 154
               |::|:.|...|:||  ....:||    ::|..||.:|||||.|.||..   :...::|....
pombe   125 ---LEIDDADRDLFDRFLPTVSGEEGDLTEEKTTSLSDLIMQKINEAEARARGEYIPSAEEEENA 186

  Fly   155 IEEIDPKVKEMYEGVRDVLKRYRSGKIPKAFKIIPKLRNWEQILFITEPHNWSAAAMFQGTRIFC 219
            :..:.|||.|:|..|..:|.:||||||||||||||.|.|||.||::|.|..|:..|.::.||||.
pombe   187 LPPLPPKVIEVYSKVGVLLSKYRSGKIPKAFKIIPTLSNWEDILYLTRPDMWTPHACYEATRIFI 251

  Fly   220 SVLSQAMAQRFYNLVLLPRVRDDLCEYKKLNMHLYNALKRALFKPAAFMKGIILPLLEGGDCTLR 284
            |.|....||.|..:::|.|||||:.|.||||.|||.|||:||:||:::.||.:.||:: .:||||
pombe   252 SNLKPVQAQHFLTVIILERVRDDIRENKKLNYHLYMALKKALYKPSSWFKGFLFPLVQ-ENCTLR 315

  Fly   285 EAIIFGSVVARSSIPVLHSSACLLKICEMAYSGANSIFIRYFLDKRYALPYRVVDAAVFHFLRFE 349
            ||.|.||::.:.|:|||||:|.||::.|...|||.|:|||..|||:|||||:|:|:.||:|:|::
pombe   316 EAAIIGSILQKVSVPVLHSAAALLRLTEFDLSGATSVFIRILLDKKYALPYKVLDSLVFYFMRWK 380

  Fly   350 NDKRELPVLWHQSLLTFAQRYKNDISSEQRDALLQLLKKKSHFKITPDVRRELQAASCRDVEM 412
            :.:|.|.||.|||:|.||||||.||:.||:||||::::.|.|:.|.|::||||..::.|..|:
pombe   381 SLERPLAVLEHQSMLVFAQRYKFDITPEQKDALLEVVRLKGHYSIGPEIRRELLNSASRGEEI 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bys	NP_511074.1	Bystin	128..412	CDD:283057	147/286 (51%)
SPBC13G1.09	NP_596559.1	Bystin	154..443	CDD:283057	148/289 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	291	1.000	Domainoid score	I278
eggNOG	1	0.900	-	-		E1_KOG3871
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2991
Inparanoid	1	1.050	313	1.000	Inparanoid score	I569
OMA	1	1.010	-	-		QHG53886
OrthoFinder	1	1.000	-	-		FOG0005208
OrthoInspector	1	1.000	-	-		oto101503
orthoMCL	1	0.900	-	-		OOG6_102261
Panther	1	1.100	-	-	LDO	PTHR12821
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1724
SonicParanoid	1	1.000	-	-		X3721
TreeFam	1	0.960	-	-
	14	13.860