DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bys and AgaP_AGAP002923

DIOPT Version :9

Sequence 1:	NP_511074.1	Gene:	bys / 31701	FlyBaseID:	FBgn0010292	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	XP_311981.5	Gene:	AgaP_AGAP002923 / 1273040	VectorBaseID:	AGAP002923	Length:	491	Species:	Anopheles gambiae

Alignment Length:	450	Identity:	269/450 - (59%)
Similarity:	337/450 - (74%)	Gaps:	27/450 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKPKKANV--ATIKNVNLEKQITEGRVAKNKNKDKVKLRAEESANIDARSSQKILAAAKLQQLE 63
            |||.|...:  .|....:.::|..||||:|...:.|::|||||...:|:::|::|||.|:.||.|
Mosquito     1 MGKSKAHRIKKLTGPKSSFDEQPNEGRVSKKAKQPKIRLRAEEGNYVDSKTSKRILAVARKQQAE 65

  Fly    64 LD--EENF---PSLVTVKKVNFSLNDGHVKEDEEVNETD--------LMADLDMDEDDVAAFERF 115
            |:  :.:|   |......|....|:|....::.::.|.|        |..|:.:.|:|..|.:.|
Mosquito    66 LNFLDSSFGPTPQESAAVKKRQRLDDRGSSDESDLEEHDEGDIDGDNLFDDIKISEEDERALQMF 130

  Fly   116 QQPAQEGKRTLHLSKMIMQKIQEKEADIHTKISDEGSLKIEEIDPKVKEMYEGVRDVLKRYRSGK 180
            |.  ::|.:|..|:.:|::|:.||:.:|.|:.||..|||::||||.|:|||:||||||||||:||
Mosquito   131 QN--KDGTKTRTLADIILEKMTEKQTEIQTQFSDNASLKLDEIDPNVREMYKGVRDVLKRYRNGK 193

  Fly   181 IPKAFKIIPKLRNWEQILFITEPHNWSAAAMFQGTRIFCSVLSQAMAQRFYNLVLLPRVRDDLCE 245
            ||||||:|||||||||.|:||||..||||||||.||:|||.|:|.||||||||||||||||||.|
Mosquito   194 IPKAFKLIPKLRNWEQFLYITEPQQWSAAAMFQATRLFCSGLTQHMAQRFYNLVLLPRVRDDLAE 258

  Fly   246 YKKLNMHLYNALKRALFKPAAFMKGIILPLLEGGDCTLREAIIFGSVVARSSIPVLHSSACLLKI 310
            |.:||.:||.:||:||||||||||||:|||||.||||||||||.|||::.:||||||::||||||
Mosquito   259 YGRLNFYLYRSLKKALFKPAAFMKGIVLPLLEAGDCTLREAIIIGSVISCTSIPVLHTAACLLKI 323

  Fly   311 CEMAYSGANSIFIRYFLDKRYALPYRVVDAAVFHFLRFENDKRELPVLWHQSLLTFAQRYKNDIS 375
            |||.||||.|:|||..||||||||||||||||||||:||.||||||.|||::|||||||||||||
Mosquito   324 CEMEYSGACSVFIRIILDKRYALPYRVVDAAVFHFLKFEQDKRELPTLWHKALLTFAQRYKNDIS 388

  Fly   376 SEQRDALLQLLKKKSHFKITPDVRRELQAASCRDVEMMETDNGLAGQPAKMYTDADVEYE 435
            ||||||||.|||||||.||||::|||||||.|||||:        ||  .:..:.:||:|
Mosquito   389 SEQRDALLHLLKKKSHPKITPEIRRELQAAQCRDVEV--------GQ--SLALEGEVEFE 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bys	NP_511074.1	Bystin	128..412	CDD:283057	220/283 (78%)
AgaP_AGAP002923	XP_311981.5	Bystin	138..425	CDD:283057	221/286 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	458	1.000	Domainoid score	I1555
eggNOG	1	0.900	-	-		E1_KOG3871
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2991
Inparanoid	1	1.050	510	1.000	Inparanoid score	I2972
OMA	1	1.010	-	-		QHG53886
OrthoDB	1	1.010	-	-		D1193442at2759
OrthoFinder	1	1.000	-	-		FOG0005208
OrthoInspector	1	1.000	-	-		oto109301
Panther	1	1.100	-	-	LDO	PTHR12821
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3721
TreeFam	1	0.960	-	-
	13	12.940