Protein Alignment RpS6 and RPS6

DIOPT Version :10

• Sequence 1: NP_511073.1
• Gene: RpS6 / 31700
• FlyBaseID: FBgn0261592
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_001001.2
• Gene: RPS6 / 6194
• HGNCID: 10429
• Length: 249
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 187/250 - (74%)
• Similarity: 214/250 - (85%)
• Gaps: 3/250 - (1%)

  Fly     1 MKLNVSYPATGCQKLFEVVDEHKLRVFYEKRMGQVVEADILGDEWKGYQLRIAGGNDKQGFPMKQ 65
            ||||:|:||||||||.||.||.|||.||||||...|.||.||:|||||.:||:||||||||||||
Human     1 MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRISGGNDKQGFPMKQ 65

  Fly    66 GVLTHGRVRLLLKKGHSCYRPRRTGERKRKSVRGCIVDANMSVLALVVLKKGEKDIPGLTDTTIP 130
            ||||||||||||.|||||||||||||||||||||||||||:|||.||::||||||||||||||:|
Human    66 GVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVP 130

  Fly   131 RRLGPKRASKIRKLYNLSKEDDVRRFVVRRPLPAKDNKKATSKAPKIQRLITPVVLQRKHRRIAL 195
            |||||||||:||||:|||||||||::|||:|| .|:.||..:||||||||:||.|||.|.|||||
Human   131 RRLGPKRASRIRKLFNLSKEDDVRQYVVRKPL-NKEGKKPRTKAPKIQRLVTPRVLQHKRRRIAL 194

  Fly   196 KKKRQIASKEASADYAKLLVQRKKESKAKREE--AKRRRSASIRESKSSVSSDKK 248
            ||:|...:||.:|:|||||.:|.||:|.||:|  |||||.:|:|.|.|...|.:|
Human   195 KKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpS6	NP_511073.1	Ribosomal_S6e	1..222	CDD:469996	172/220 (78%)
RPS6	NP_001001.2	Ribosomal_S6e	1..215	CDD:469996	169/214 (79%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..249		16/31 (52%)