DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpS6 and rps6

DIOPT Version :9

Sequence 1:	NP_511073.1	Gene:	RpS6 / 31700	FlyBaseID:	FBgn0261592	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_989152.1	Gene:	rps6 / 394757	XenbaseID:	XB-GENE-1003287	Length:	249	Species:	Xenopus tropicalis

Alignment Length:	250	Identity:	186/250 - (74%)
Similarity:	214/250 - (85%)	Gaps:	3/250 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLNVSYPATGCQKLFEVVDEHKLRVFYEKRMGQVVEADILGDEWKGYQLRIAGGNDKQGFPMKQ 65
            ||||:|:||||||||.||.||.|||.||||||...|.||.||||||||.:||:||||||||||||
Frog     1 MKLNISFPATGCQKLIEVEDERKLRTFYEKRMATEVAADPLGDEWKGYVVRISGGNDKQGFPMKQ 65

  Fly    66 GVLTHGRVRLLLKKGHSCYRPRRTGERKRKSVRGCIVDANMSVLALVVLKKGEKDIPGLTDTTIP 130
            ||||||||||||.|||||||||||||||||||||||||||:|||.||:::|||||||||||.|:|
Frog    66 GVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVRKGEKDIPGLTDNTVP 130

  Fly   131 RRLGPKRASKIRKLYNLSKEDDVRRFVVRRPLPAKDNKKATSKAPKIQRLITPVVLQRKHRRIAL 195
            |||||||||:||||:|||||||||::|||:|| ||:.||..:||||||||:||.|||.|.|||||
Frog   131 RRLGPKRASRIRKLFNLSKEDDVRQYVVRKPL-AKEGKKPRTKAPKIQRLVTPRVLQHKRRRIAL 194

  Fly   196 KKKRQIASKEASADYAKLLVQRKKESKAKREE--AKRRRSASIRESKSSVSSDKK 248
            ||:|...:||.:::|||||.:|.||:|.||:|  |||||.:|:|.|.|...|.:|
Frog   195 KKQRTQKNKEEASEYAKLLAKRTKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpS6	NP_511073.1	Ribosomal_S6e	1..222	CDD:294602	171/220 (78%)
rps6	NP_989152.1	Ribosomal_S6e	1..215	CDD:382290	168/214 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	223	1.000	Domainoid score	I2520
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H85949
Inparanoid	1	1.050	345	1.000	Inparanoid score	I2267
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1326714at2759
OrthoFinder	1	1.000	-	-		FOG0003187
OrthoInspector	1	1.000	-	-		oto102870
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1248
SonicParanoid	1	1.000	-	-		X2145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090