DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpS6 and rps-6

DIOPT Version :9

Sequence 1:	NP_511073.1	Gene:	RpS6 / 31700	FlyBaseID:	FBgn0261592	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_493435.1	Gene:	rps-6 / 173260	WormBaseID:	WBGene00004475	Length:	246	Species:	Caenorhabditis elegans

Alignment Length:	250	Identity:	148/250 - (59%)
Similarity:	183/250 - (73%)	Gaps:	7/250 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLNVSYPATGCQKLFEVVDEHKLRVFYEKRMGQVVEADILGDEWKGYQLRIAGGNDKQGFPMKQ 65
            |:||.:|||||.||.|||.:|.|||:|:||||.|.|..|.||||||||.:||.||||||||||||
Worm     1 MRLNFAYPATGLQKSFEVDEEKKLRLFFEKRMSQEVAIDALGDEWKGYVVRIGGGNDKQGFPMKQ 65

  Fly    66 GVLTHGRVRLLLKKGHSCYRPRRTGERKRKSVRGCIVDANMSVLALVVLKKGEKDIPGLTDTTIP 130
            |:||:||||||||||.||||.|:.||||||||||||||||||.|:||::|||:.:|.||||:.:|
Worm    66 GILTNGRVRLLLKKGQSCYRERKNGERKRKSVRGCIVDANMSALSLVIVKKGDGEIEGLTDSVLP 130

  Fly   131 RRLGPKRASKIRKLYNLSKEDDVRRFVVRRPLPAKDNKKATSKAPKIQRLITPVVLQRKHRRIAL 195
            |:||||||||||||:||:|.|||.::|:.......|....|. ||||||||||..:.||...:..
Worm   131 RKLGPKRASKIRKLFNLTKHDDVTKYVITHDKTFPDGVTKTI-APKIQRLITPARIARKKYLLRQ 194

  Fly   196 KKKRQIASKEASADYAKLLVQRKKESKAKREEAK--RRRSASIRESKSSVSSDKK 248
            |:.::|..::.:|.|.|||.:..||    ..:||  ||||::...|:|.|....|
Worm   195 KRNQKIKMRDDAAAYHKLLAKYSKE----EHDAKIARRRSSASHHSESEVKKTSK 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpS6	NP_511073.1	Ribosomal_S6e	1..222	CDD:294602	138/220 (63%)
rps-6	NP_493435.1	Ribosomal_S6e	1..219	CDD:294602	136/218 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157434
Domainoid	1	1.000	197	1.000	Domainoid score	I1822
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H85949
Inparanoid	1	1.050	282	1.000	Inparanoid score	I1750
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53585
OrthoDB	1	1.010	-	-		D1326714at2759
OrthoFinder	1	1.000	-	-		FOG0003187
OrthoInspector	1	1.000	-	-		oto19540
orthoMCL	1	0.900	-	-		OOG6_100737
Panther	1	1.100	-	-	LDO	PTHR11502
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1248
SonicParanoid	1	1.000	-	-		X2145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940