Protein Alignment p115 and uso1

DIOPT Version :9

• Sequence 1: NP_001284992.1
• Gene: p115 / 31698
• FlyBaseID: FBgn0040087
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_956449.1
• Gene: uso1 / 393124
• ZFINID: ZDB-GENE-040426-688
• Length: 956
• Species: Danio rerio
• Alignment Length: 931
• Identity: 428/931 - (45%)
• Similarity: 575/931 - (61%)
• Gaps: 137/931 - (14%)

  Fly     1 MEFLKSGIKTVLGSTEPGQQPSAAETVEKLVDRVYSSTLLEDRRDACRALKALSRKYRIEVGAQG 65
            |:||:.    |:||...|.||:.|||::||.|||.|||||||||||.||||:||:|||:|||...
Zfish     1 MDFLRG----VMGSKPAGPQPTGAETIQKLCDRVASSTLLEDRRDAVRALKSLSKKYRLEVGTMS 61

  Fly    66 MPPLVQVLQNDGQDAEIISYALDTLCNVVTSEEFDEEADNPTVSV-----NVGEQFTEMFIKTPE 125
            |..||::||.|..|.||:.||||||.|:|.::|.:|:.|:...:.     ::|.|||:.||:.||
Zfish    62 MDHLVRILQTDRSDTEILGYALDTLYNIVCNDEEEEQDDSEEENQQKQEDDLGAQFTDKFIQEPE 126

  Fly   126 HVTLVMGYLDEYDFRVRRAAIQLITSLISNKTRELQDLILVSPMGVSKLMDLLTDSREVIRNDVL 190
            ::||::..|:|:||.||...::|:|:|:.::..::|.::||||||||:|||||.|||||||||.|
Zfish   127 NITLLLTLLEEFDFHVRWPGVKLLTALLKSQCAQVQGIVLVSPMGVSRLMDLLADSREVIRNDGL 191

  Fly   191 LLLIELTKGNSNIQKIVAFENAFDRLFEIVREEGCSDGGIVVEDCLILLLNLLKNNSSNQQFFKE 255
            |||.:|||||:.|||||||||||:||.:|:.|||.|||||||||||:|||||||||||||.||||
Zfish   192 LLLQQLTKGNAAIQKIVAFENAFERLLDIITEEGSSDGGIVVEDCLLLLLNLLKNNSSNQNFFKE 256

  Fly   256 GSYIQRLSPMFELSQDAEEVGWSPQKVSNFHCLLQVVRALVTPSNQQQVVAACQRVMQKSRLLHA 320
            |||||::.|.||:..|  ..|||.|||:|.|.:||:||.||:|.|.....|:||:.|.:..||..
Zfish   257 GSYIQKMKPWFEVGDD--NSGWSAQKVTNLHLMLQLVRVLVSPVNSPGATASCQKAMFQCGLLQQ 319

  Fly   321 LCEILMSSGVPADILTETINAVAEVVRGDRDNQDELGRVMAPSSPPRPAIVVLLMSMINEKQLLA 385
            ||.|||::||||||||||||.|:||:||...|||....|.|||:|||||||||||||:||:|...
Zfish   320 LCTILMATGVPADILTETINTVSEVIRGSEVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFV 384

  Fly   386 LRCAVLYCFECFLYRNADGQRAVVQTLLPSSASDVSALSTGQLLCTGLFSTDALANWFSAVALMH 450
            |||||||||:||||:|..||..:|.|||||:. |.:::|.|||||.||||.|:|:||.:||||.|
Zfish   385 LRCAVLYCFQCFLYKNQKGQGEIVATLLPSTI-DANSISAGQLLCGGLFSADSLSNWCAAVALAH 448

  Fly   451 SLVENVALKEELLRVLLATPGGQKPITLLEQCTNLMQQ------ERYRLQSKVGLLMLLSLWLAH 509
            :|.:|:..||:||||.|||..|:.|::||:||||::.|      ...|:|:||||||||..|:::
Zfish   449 ALQDNLTQKEQLLRVQLATSLGKPPVSLLQQCTNILSQGDKLNRRGSRVQTKVGLLMLLCTWISN 513

  Fly   510 CPGAVKALLETQGTMAYLTAQLCSN-EHDEREFLVQGMCAFLMGLCIQFNDNSLPGQKREDISQL 573
            ||.||...|..|..:.:||.|:..| ..|||  ||||:||.|:|:||.:|||||....:|.:.||
Zfish   514 CPIAVMHFLHNQDNVPFLTGQISENLGEDER--LVQGLCALLLGICIYYNDNSLENYTKEKLKQL 576

  Fly   574 IIKRIGQESFCSKLAEVSRHEAYSRACKQAQIRAKSAGELLLDFEYCKLYKGLEALIAKLV--SG 636
            |.||||:|:|..|||.:::||.||||.::.|....:...:|.|.|:.||.|.||.:|.|.|  |.
Zfish   577 IEKRIGKENFVEKLAFITKHELYSRAAQKPQPAFSTPEHMLFDHEFTKLVKELEGMITKAVLRSS 641

  Fly   637 FDVDGIELTELTLSSEASALVSQYKGIIRGMDAQIQAL--------------------------- 674
            .:....|..:.||....| :|:|||.:||..|:||..|
Zfish   642 EEEKKEEEVKKTLEQHDS-IVTQYKELIREQDSQINELKKQVTALTSQTENLESTITQQLSQIQQ 705

  Fly   675 ----------------QQSSKELE---------QENAELKEKLGE----EQSLKAQLLDQNTL-- 708
                            ||:..:.|         :|.::|:|:|.|    .|.|:.||.::::|
Zfish   706 HKDQYNILKLKLGKDTQQAGNQAEAAHVNGLQPEELSQLRERLEEVQRQNQLLQTQLTEKDSLIT 770

  Fly   709 --------------------------LKAQLGASTGQVQSAQ--------GAE---ATPPNE--- 733
                                      |||||.:.|.::...|        |:|   |.|..|
Zfish   771 SLKAEGVPSVEDSTSEVTELRKEVEGLKAQLQSQTAEITQLQNERQELLRGSEPTVAVPAEESVY 835

  Fly   734 -EELNAARYQANMYFAENIRLTKELET-LRQQLSAEKQSADAA-------------QDSLAAMQK 783
             |::.....:.:....||.:|..|::| |..:.|.||..|.|.             |..:...:|
Zfish   836 KEKIAELESRLSAQTTENQKLKGEVKTLLESKESMEKDLASATSTSAILQAEKNKLQQEVQESKK 900

  Fly   784 DQEDLLELLADQEAKLTRYEE 804
            :|:|||.|||||:.|:...::
Zfish   901 EQDDLLMLLADQDQKILNLKQ 921

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p115	NP_001284992.1	Uso1_p115_head	354..632	CDD:309827	151/284 (53%)
		Uso1_p115_C	690..832	CDD:309829	44/176 (25%)
uso1	NP_956449.1	Uso1_p115_head	351..637	CDD:282693	154/288 (53%)
		COG1340	648..934	CDD:224259	63/275 (23%)
		TBPIP	<736..818	CDD:284512	17/81 (21%)
		Uso1_p115_C	831..932	CDD:282695	25/91 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595991
Domainoid	1	1.000	322	1.000	Domainoid score	I1196
eggNOG	1	0.900	-	-		E1_KOG0946
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2754
Inparanoid	1	1.050	737	1.000	Inparanoid score	I586
OMA	1	1.010	-	-		QHG55450
OrthoDB	1	1.010	-	-		D1273987at2759
OrthoFinder	1	1.000	-	-		FOG0004607
OrthoInspector	1	1.000	-	-		oto38727
orthoMCL	1	0.900	-	-		OOG6_103848
Panther	1	1.100	-	-	LDO	PTHR10013
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1694
SonicParanoid	1	1.000	-	-		X3226
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800