Protein Alignment p115 and uso1

DIOPT Version :10

• Sequence 1: NP_572417.1
• Gene: p115 / 31698
• FlyBaseID: FBgn0040087
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_001417951.1
• Gene: uso1 / 2542708
• PomBaseID: SPAC29E6.03C
• Length: 1091
• Species: Schizosaccharomyces pombe
• Alignment Length: 892
• Identity: 226/892 - (25%)
• Similarity: 383/892 - (42%)
• Gaps: 144/892 - (16%)

  Fly     1 MEFLKSGIKTVLGSTEPGQQPSAAETVEKLVDRVYSSTLLEDRRDACRALKALSRKYRIEVGAQG 65
            |:........:|   .|.:...|.||:.||.||:..:||.|||:.|...:|:.:|:::..|.|.|
pombe     1 MDIFHKSYNVIL---SPPKVQQADETISKLCDRLEHATLFEDRKAAALGIKSFAREFKELVAAHG 62

  Fly    66 MPPLVQVLQNDGQDAEIISYALDTLCNVVTSEEFDEEADNPTVSVNVGEQFTEMFIKTPEHVTLV 130
            :..::|.|..|..|.|::...|:| |.::|..:.|..|.      :.|....:.||...:::..:
pombe    63 LKGIIQSLHRDYDDPELLKVTLET-CLILTRHDDDSRAS------DTGLWIADQFILNQDNIQCL 120

  Fly   131 MGYLDEYDFRVRRAAIQLITSLISNKTRELQDLILVSPMGVSKLMDLLTDSREVIRNDVLLLLIE 195
            :..:...||.||..:::|.::::|.:..||:|.:...|..:|.:|..|.||.|.:||..|..|.|
pombe   121 LQSISHKDFYVRLYSVELFSAILSCRPTELKDCLQTFPSAISSIMVPLRDSIEPVRNADLYFLSE 185

  Fly   196 LTKGNSNIQKIVAFENAFDRLFEIVREEGCSDGGIVVEDCLILLLNLLKNNSSNQQFFKEGSYIQ 260
            |.|..::|||:|.|||||:.||.::..||..||||:..:.|..|..|||:|.|||.:|:|.::|.
pombe   186 LVKDCTSIQKLVVFENAFETLFSLLENEGGVDGGIIALEALKFLNVLLKDNISNQNYFRESNHIP 250

  Fly   261 RLSPMFELSQDAEEVG-WSPQKVSNFHCLLQVVRAL--VTP-------SNQQQVVAACQRVMQKS 315
            .|..:  ||.|....| |...:|   .|:::.:.||  :.|       :||..||:.
pombe   251 SLLKL--LSVDTFVDGTWDTSRV---QCVIEALYALQSLVPIGLSSSIANQNAVVSN-------- 302

  Fly   316 RLLHALCEILMSSGVPADILTETINAVAEVVRGDRDNQDELGRVMAPSSPPRPAIVVLLMSMINE 380
               |.: ::|::.....|:|...:..::.:.         |..|:..::..:.:.|.  .:..:.
pombe   303 ---HGI-DVLLTLATHPDLLFFDVQKISWIT---------LAHVVYSNARAQNSFVD--STFFDI 352

  Fly   381 KQLLALRCAVLYCFECFLYRNADGQRAVVQTLLPSSASDVSALST-------------------- 425
            |....|.|...|   .||...:...|..|...|.|..|:...||:
pombe   353 KNTDVLTCLFDY---LFLSSISPSHRYSVAFFLRSLTSENDELSSKFLKQIIHAYTHKQDNRLNI 414

  Fly   426 --GQLLCTGLFSTDALANWFSAVALMHSLVENVALKEELLRVLL-------ATPGGQKPITLLEQ 481
              |.|....|...|...|||::..|.:.:::|...|..|..:.|       .....:..:|.: |
pombe   415 IQGYLDLVHLSDQDQYDNWFTSTILTYLVIDNDQRKYLLCSIPLFQDMDNDEDSESEDKVTFI-Q 478

  Fly   482 C--TNLMQQERYR--LQSKVGLLMLLSLWLAHCPGAVKALL-ETQGTMAYLTAQLCSNEHDEREF 541
            |  |.|:...|:.  ||:.||.|.||...:...|.:||..| |:.....:|||.:  :|......
pombe   479 CVSTKLIATLRHENALQNCVGYLTLLIALVYGNPDSVKDFLSESSILQTFLTALM--DESSSANS 541

  Fly   542 LVQGMCAFLMGLCIQFNDNSLPGQKREDISQLIIKRIGQESFCSKLAEVSRHEAYSRACKQAQIR 606
            ::|||.|..:.|...:.....|..| .|:...|...:.::.|.::|..:.:.|.........:..
pombe   542 VIQGMIAVFLSLVYYYCPIESPVSK-SDVYNAITSAVKRDVFINRLQRLRKDELIRDHVPVNEAE 605

  Fly   607 AKSAGELLLDFEYCKLYKG----LEALIAKLVSGFDVDGIELTELTLSSEASALVSQYKGIIRGM 667
            ..:..::|.|..:...:|.    |:..|......|:....|:..|....||.   .|.|.:...:
pombe   606 DGNCNDILFDTTFVNFFKDNFYRLKHAIDDAADAFNTKIGEINTLDAFDEAQ---KQLKSLREEI 667

  Fly   668 DAQIQALQQSSKELEQENAELKEKLG------EEQSLKA-----QLLD-QNTL--LKAQLGASTG 718
            |...:||..|.||...:..:|.|.|.      |||:..|     :||| |..|  |:.:|..:..
pombe   668 DNTKEALDLSVKERSIQEEKLNESLKTSKTNLEEQTQLAEKYHEELLDNQQKLYDLRIELDYTKS 732

  Fly   719 QVQSAQGAEATPPNEEELNAAR--YQANM--YFAENIRLTKELETLRQQ----------LSAEKQ 769
            ..:..         |||:...|  :::.:  :..|:.:|||:|:.::.|          |.:|.:
pombe   733 NCKQM---------EEEMQVLREGHESEIKDFIEEHSKLTKQLDDIKNQFGIISSKNRDLLSELE 788

  Fly   770 SADAAQDSLAAMQ---KDQEDLLELL--------ADQEAKLTRYEEA 805
            .:.:..:||||::   |..|:.|.||        ||.|:......||
pombe   789 KSKSLNNSLAALESKNKKLENDLNLLTEKLNKKNADTESFKNTIREA 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p115	NP_572417.1	Arm_vescicular	275..334	CDD:465861	13/68 (19%)
		Uso1_p115_head	361..632	CDD:461460	65/308 (21%)
		Uso1_p115_C	690..832	CDD:461461	39/155 (25%)
uso1	NP_001417951.1	Uso1_p115_head	354..633	CDD:461460	62/285 (22%)
		SMC_N	<654..1009	CDD:481474	50/194 (26%)