Protein Alignment p115 and uso-1

DIOPT Version :10

• Sequence 1: NP_572417.1
• Gene: p115 / 31698
• FlyBaseID: FBgn0040087
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_001040973.1
• Gene: uso-1 / 178311
• WormBaseID: WBGene00010713
• Length: 941
• Species: Caenorhabditis elegans
• Alignment Length: 873
• Identity: 284/873 - (32%)
• Similarity: 463/873 - (53%)
• Gaps: 107/873 - (12%)

  Fly    13 GSTEPGQQPSAAETVEKLVDRVYSSTLLEDRRDACRALKALSRKYRIEVGAQGMPPLVQVLQNDG 77
            |..:...:.:.||.||.||:|..:.|..||||||.|.||.:::|||:.||..||...:.||:.|.
 Worm    76 GGQQDEDEDNGAEYVETLVERAETCTAPEDRRDALRGLKGVAKKYRLAVGTMGMNAFIDVLETDR 140

  Fly    78 QDAEIISYALDTLCNVVTSEEFDEEADNPTVSVNVGEQFTEMFIKTPEHVTLVMGYLDEYDFRVR 142
            .:.|.::..|||:..|:::::...|:|      .:||:..|:.||....::.|:..::::|..||
 Worm   141 MNTEAMTIVLDTMAIVLSTDDDSSESD------ELGERLAEVMIKRKGFISSVLCAVEQFDIGVR 199

  Fly   143 RAAIQLITSLISNKTRELQDLILVSPMGVSKLMDLLTDSREVIRNDVLLLLIELTKGNSNIQKIV 207
            |.|||||::|:.::..|:|..::..|.|::||:|::.|:||:|||:.:|::.||::.||.:|:::
 Worm   200 RTAIQLISNLLRHRGTEVQKAVMEHPQGIAKLVDVIHDNREIIRNEAILMICELSRANSQVQQLL 264

  Fly   208 AFENAFDRLFEIVREEGCSDGGIVVEDCLILLLNLLKNNSSNQQFFKEGSYIQRLSPMF------ 266
            |::|.|..|..|:..|...  .||:|||:.::||||:.::.|||.|:|..::.||..:.
 Worm   265 AYDNIFLDLLNIIETEPLD--SIVIEDCMFVMLNLLRKHAMNQQIFREDQFVARLGKILHTFLYG 327

  Fly   267 -ELSQDAEEVGWSPQKVSNFHCLLQVVRALVTPSNQQQVVAACQRVMQKSRLLHALCEILMSS-G 329
             |.::|.|...|:.|:.:|...|||::|.||:|.|..:...|.|:|:.::::|..||.:|:|. |
 Worm   328 NEETEDIEVTEWAKQRTANVIFLLQIIRTLVSPDNTSENTHAAQKVLNQTKILEELCRVLLSEIG 392

  Fly   330 VPADILTETINAVAEVVRGDRDNQDELGRVMAPSSP--PRPAIVVLLMSMINEKQLLALRCAVLY 392
            ...:||||:|..|||.:||:..||:.....:..:..  ||.::||||:||..|||...|||||.|
 Worm   393 ASVEILTESIIVVAEAIRGNYTNQELFANTVLDNGEDVPRTSLVVLLISMTAEKQPYKLRCAVFY 457

  Fly   393 CFECFLYRNADGQRAVVQTLLPSSASDVSALSTGQLLCTGLFSTDALANWFSAVALMHSLVENVA 457
            ||..:|:.|..|:..|::||||.|.:..|:|:||.|:...:.|.:::..||..|.|||.|.:...
 Worm   458 CFLSYLFDNEFGKARVIETLLPQSHNSSSSLTTGALILQAISSAESVQAWFGCVTLMHCLYDVDH 522

  Fly   458 LKEELLRVLLATPGGQKPITLLEQ-CTNLMQQERYRLQSKVGLLMLLSLWLAHCPGAVKALLETQ 521
            |.|:||||.|.......|:|||.. |..|:.....|.|::.||||||..||.:||.||...:...
 Worm   523 LSEQLLRVNLTVVTEDPPLTLLNHVCQLLVSTGNRRPQTRAGLLMLLGTWLQNCPAAVSDFMAKD 587

  Fly   522 GTMAYLTAQL---CSNEHDEREFLVQGMCAFLMGLCIQFNDNSLPGQKREDISQLIIKRIGQESF 583
            ..:.|||..|   |....:..:.:::|:.||::..|::   |....:.|..:..||.:|:|:|..
 Worm   588 EHIQYLTTNLVDECGEGSESEQQVLRGLMAFVLLSCLK---NLQSKEARSSMEILIQRRVGKELI 649

  Fly   584 CSKLAEVSRHEAYSRACKQAQIRAKSAGELLLDFEYCKLYKGLEALIAK-LVSGFDVDGIELTEL 647
            .|.|..:||.|.:.||.::.|    ...||.|||.:.||:|.||..:|| |....:.:|
 Worm   650 LSALEGLSRTEQFVRAAQKQQ----PTNELFLDFHFVKLFKSLEGTLAKQLKPNGEFNG------ 704

  Fly   648 TLSSEASALVSQYKGIIRGMDAQIQALQQSSK----ELEQENAELKEKLGEE--QSLKAQLLD-- 704
               :...:::..||.:|:..|..|..|:|.:|    |:|:.|||::.|..|.  ::|:.:|.:
 Worm   705 ---TSNDSIIQSYKELIKRQDGDIAQLKQDNKRMSLEIEKLNAEVQNKQMEREVENLRVRLEESE 766

  Fly   705 ----QNTLLKAQLGASTGQVQS--------AQGAE-------ATPPNEEELNAARYQANM----- 745
                ||.:|.:||..|....|.        .|.|:       |..||..|...|:.|..:
 Worm   767 AFKTQNEVLNSQLVESQRLTQQWYAEAERYKQWAQQWQAYQLAQLPNGVETGLAQLQQQVNELEQ 831

  Fly   746 ------------------YFAENIRLTKELETLR----------QQLSAE--------KQSADAA 774
                              |.:||..|...|....          :||:.:        :....|.
 Worm   832 QLGFGYQAFEQQSQTMLHYTSENANLKDRLAKTEAALAEANYKIEQLNLKPISNGIVVEHEPQAD 896

  Fly   775 QDSLAAMQKDQEDLLELLADQEAKLTRY 802
            .:..:.::::||:||.|||||..|::.|
 Worm   897 SEEFSKLKQEQEELLMLLADQHNKMSAY 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p115	NP_572417.1	Arm_vescicular	275..334	CDD:465861	20/59 (34%)
		Uso1_p115_head	361..632	CDD:461460	102/276 (37%)
		Uso1_p115_C	690..832	CDD:461461	38/177 (21%)
uso-1	NP_001040973.1	Arm_vescicular	339..389	CDD:465861	18/49 (37%)
		Uso1_p115_head	414..696	CDD:461460	106/288 (37%)
		PRK11281	739..>879	CDD:481316	29/139 (21%)
		Uso1_p115_C	815..941	CDD:461461	22/110 (20%)