Protein Alignment p115 and uso1

DIOPT Version :9

• Sequence 1: NP_001284992.1
• Gene: p115 / 31698
• FlyBaseID: FBgn0040087
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: XP_004911135.2
• Gene: uso1 / 100488011
• XenbaseID: XB-GENE-1013306
• Length: 960
• Species: Xenopus tropicalis
• Alignment Length: 939
• Identity: 415/939 - (44%)
• Similarity: 559/939 - (59%)
• Gaps: 145/939 - (15%)

  Fly     1 MEFLKSGIKTVLGSTE-PGQQPSAAETVEKLVDRVYSSTLLEDRRDACRALKALSRKYRIEVGAQ 64
            |.||:.    |:|..: .|.|.|..:|::||.|||.|:|||:|||||.||||:||:|||.:|..|
 Frog     1 MNFLRG----VMGGQQTSGAQQSGTQTIQKLCDRVASATLLDDRRDAVRALKSLSKKYRFDVATQ 61

  Fly    65 GMPPLVQVLQNDGQDAEIISYALDTLCNVVTS---EEFDEEADNPTVSV-NVGEQFTEMFIKTPE 125
            .|..|:.|||.|..|:|||.||||||.|::::   |..:.|.:|..::. ::|.||:|.||...|
 Frog    62 AMDHLINVLQTDRSDSEIIGYALDTLYNIMSNDADETAESEDENQQIAPDDLGVQFSETFINQQE 126

  Fly   126 HVTLVMGYLDEYDFRVRRAAIQLITSLISNKTRELQDLILVSPMGVSKLMDLLTDSREVIRNDVL 190
            ::||::..|:|:||.||...::|:|:|:.::..::|..:||||||||:|||||.|||||||||.|
 Frog   127 NITLLLSLLEEFDFHVRWPGVKLLTTLLKHQGPQVQQTVLVSPMGVSRLMDLLDDSREVIRNDGL 191

  Fly   191 LLLIELTKGNSNIQKIVAFENAFDRLFEIVREEGCSDGGIVVEDCLILLLNLLKNNSSNQQFFKE 255
            |||.:|||.|:.||||||||||::||.:|:.|||.|||||||||||:||.||||.|:|||.||||
 Frog   192 LLLQQLTKSNAAIQKIVAFENAYERLLDIITEEGSSDGGIVVEDCLLLLQNLLKYNNSNQNFFKE 256

  Fly   256 GSYIQRLSPMFELSQDAEEVGWSPQKVSNFHCLLQVVRALVTPSNQQQVVAACQRVMQKSRLLHA 320
            ||||||:.|.||:..|  ..|||.|||:|.|.:||:||.||:|.|......:||:.|.:..||..
 Frog   257 GSYIQRMKPWFEVGDD--NSGWSAQKVTNLHLMLQLVRVLVSPVNPPGATNSCQKSMFQCGLLQQ 319

  Fly   321 LCEILMSSGVPADILTETINAVAEVVRGDRDNQDELGRVMAPSSPPRPAIVVLLMSMINEKQLLA 385
            ||.|||::||||||||||||.|:||:||.:.|||....|.|||:|||||||||||||:||:|...
 Frog   320 LCIILMATGVPADILTETINTVSEVIRGSQVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFV 384

  Fly   386 LRCAVLYCFECFLYRNADGQRAVVQTLLPSSASDVSALSTGQLLCTGLFSTDALANWFSAVALMH 450
            |||||||||:||||:|..||..:|.|||||:. |.:|||.|||||.||||||:|:||.:||||.|
 Frog   385 LRCAVLYCFQCFLYKNEKGQGEIVATLLPSTI-DANALSAGQLLCGGLFSTDSLSNWCAAVALAH 448

  Fly   451 SLVENVALKEELLRVLLATPGGQKPITLLEQCTNLMQQ------ERYRLQSKVGLLMLLSLWLAH 509
            :|::|...||:||||.|||..|..|::||:||||::.|      ...::|::|||||||..||.:
 Frog   449 ALLDNATQKEQLLRVQLATSIGNPPVSLLQQCTNILSQGDKLIRRGSKVQTRVGLLMLLCTWLTN 513

  Fly   510 CPGAVKALLETQGTMAYLTAQLCSNEHDEREFLVQGMCAFLMGLCIQFNDNSLPGQKREDISQLI 574
            ||.||...|.....:.:||||:..|..:| |.||||:||.|:|:||.:|||||....::.:.|||
 Frog   514 CPIAVTHFLHNAANVPFLTAQISENLGEE-EHLVQGLCALLLGICIYYNDNSLENNTKDKLKQLI 577

  Fly   575 IKRIGQESFCSKLAEVSRHEAYSRACKQAQIRAKSAGELLLDFEYCKLYKGLEALIAKLVSGFDV 639
            .||||:|:|..||..:::||.||:|.::.|....|...:|.|.|:.||.|.||.:|.|.:.....
 Frog   578 EKRIGKENFTEKLGFITKHEFYSKAAQKPQPTFSSPDHMLFDHEFTKLVKELEVVITKAIYKSSE 642

  Fly   640 DGIELTELTLSSEA-SALVSQYKGIIRGMDAQIQALQQSSKEL----EQENAELKEKLGEEQSLK 699
            :..:..|:..|.|. .::||.||.|||..|.:::..:|:...|    ||..:.:..:||:.|..|
 Frog   643 EDKKEEEVKKSLEQHDSIVSHYKSIIREQDIKMEEFKQTIASLQSTNEQNQSTISLQLGQIQQHK 707

  Fly   700 AQLLDQNTLLKAQLGAST------------------------GQVQ------------------- 721
                ||..|||.|||..:                        |:|:
 Frog   708 ----DQYNLLKVQLGKDSQHHGSQNSTTQMNGFQPEDVSRLKGEVEELKRQQDILQGELSEKNVL 768

  Fly   722 ---------SAQGAEATPPNEEELNAARYQANMYFAENIR------------------------- 752
                     ..|..:.|...::||...|.|.::..||..|
 Frog   769 IESLQQSQVDGQTDQMTEEIQKELETLRSQLHVQSAEINRLQAERMELLQKTETSGSLSASGDSS 833

  Fly   753 ---------------LTKELETLRQQL-------SAEKQSADAAQDSLAAMQ------------- 782
                           |.||:..|::.|       |:.||..|.||.:.|.:|
 Frog   834 VNSQSNTEMEQKVAELLKEIAGLKEHLKNQSEEKSSWKQQLDTAQSTAAILQDENQKLKQEVTES 898

  Fly   783 -KDQEDLLELLADQEAKL----TRYEEAG 806
             |:|:|||.|||||:.|:    .|.:|.|
 Frog   899 KKEQDDLLVLLADQDQKIFSLKKRLKELG 927

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p115	NP_001284992.1	Uso1_p115_head	354..632	CDD:309827	150/283 (53%)
		Uso1_p115_C	690..832	CDD:309829	50/234 (21%)
uso1	XP_004911135.2	Arm_vescicular	274..333	CDD:408541	30/58 (52%)
		Uso1_p115_head	351..637	CDD:398505	153/287 (53%)
		Smc	<654..>926	CDD:224117	61/275 (22%)
		Uso1_p115_C	836..938	CDD:398507	27/92 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	285	1.000	Domainoid score	I1581
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2754
Inparanoid	1	1.050	688	1.000	Inparanoid score	I684
OMA	1	1.010	-	-		QHG55450
OrthoDB	1	1.010	-	-		D1273987at2759
OrthoFinder	1	1.000	-	-		FOG0004607
OrthoInspector	1	1.000	-	-		oto103057
Panther	1	1.100	-	-	LDO	PTHR10013
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3226
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.080