Protein Alignment Nek2 and FMP48

DIOPT Version :10

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_011566.1
• Gene: FMP48 / 852943
• SGDID: S000003284
• Length: 369
• Species: Saccharomyces cerevisiae
• Alignment Length: 371
• Identity: 90/371 - (24%)
• Similarity: 147/371 - (39%)
• Gaps: 79/371 - (21%)

  Fly    19 YEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAKCDALVSEISVLRQLQ----HPNI- 78
            |..|..:.:|:|.|.||....:.....|.|.....:..||.   :.:|..|::.|.    ||||
Yeast     2 YTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEAN---MKNEYDVMKILSSCNPHPNIC 63

  Fly    79 --VQYYHHLVNREAKSVYI-VMECCAGGDLAQIVQRARSQRQRFEEPYI----WRVLFQLCRALQ 136
              :.:|      ...|.|| |:|.|..|||...:..|:||........|    .:::.|||.|:.
Yeast    64 SMLDFY------TDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAIS 122

  Fly   137 VCHNKIPNGTILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGR 201
            ..|:.    .|.||||||.||.|...|:.||.|:|.|....:...|.   :||.:|.:||...||
Yeast   123 FAHSL----GIAHRDIKPENILLTINGDIKLADWGHAIQSPKSNDFQ---IGTDNYRAPETFSGR 180

  Fly   202 --------KYDRKS---------DVWAVGCLVYEM----CALRPPFRGRAFDQLSEKIAQ----G 241
                    .:||.|         |.|::|..::.:    |..|.        ..|:|:..    .
Yeast   181 VSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLFRV--------SKSKKVQHLKNFD 237

  Fly   242 EFSRIPAIYSTDLQEIIAFMLAVDHEQRPGIEVIIRH--PLVVRNISELDGKF---PILVD---- 297
            ||.:.|  ::...::.:...|:..:.....:.|.::|  ..:.:::.::...|   .|:||
Yeast   238 EFEKDP--FAFIYRKYVVPRLSCGYNDEEDLHVSLQHTRQYIWQDLPDIYDVFHLCKIMVDTLLK 300

  Fly   298 -------SGEDFYTLPSGARLFEDEEEDGVHPELSSTMFTEQYSFN 336
                   |.|:|......|...:...:.....:....:|.||:|.|
Yeast   301 VSNAKERSMENFINEVDSAWNKDSSMDSCFSYQNKIDLFWEQWSVN 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	77/300 (26%)
FMP48	NP_011566.1	S_TKc	2..>223	CDD:214567	68/236 (29%)