Protein Alignment Nek2 and KIN3

DIOPT Version :9

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_009410.1
• Gene: KIN3 / 851273
• SGDID: S000000071
• Length: 435
• Species: Saccharomyces cerevisiae
• Alignment Length: 309
• Identity: 102/309 - (33%)
• Similarity: 161/309 - (52%)
• Gaps: 56/309 - (18%)

  Fly    18 DYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAKCDALVSEISVLRQLQHPNIVQYY 82
            :|:||..:|.||||:..||....|.:|...|.:.|..::..:...|::|.|:|.||:|.|||::|
Yeast    24 EYQVLEEIGRGSFGSVRKVIHIPTKKLLVRKDIKYGHMNSKERQQLIAECSILSQLKHENIVEFY 88

  Fly    83 HHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQLCRALQVCHN--KIPNG 145
            :...:.:.:.:|:.||.|:.|||:|:::..:.:.:...|..:|.:|.||..||..||.  ::|..
Yeast    89 NWDFDEQKEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTL 153

  Fly   146 T---------------ILHRDIKPANIFL---DAAGN---------------------------- 164
            |               ::|||:||.||||   |:..|
Yeast   154 TTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGS 218

  Fly   165 --------AKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRKYDRKSDVWAVGCLVYEMCA 221
                    .||||||||:.|.....||.::||||:|||||::..:.|...||:|::||:::|||:
Yeast   219 PMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCS 283

  Fly   222 LRPPFRGRAFDQLSEKIAQGEFSRIPAIYSTDLQEIIAFMLAVDHEQRP 270
            |.|||:.:.:.:|..||..|:...:|..||..|..||..|:.|:...||
Yeast   284 LHPPFQAKNYLELQTKIKNGKCDTVPEYYSRGLNAIIHSMIDVNLRTRP 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	102/309 (33%)
		S_TKc	19..281	CDD:214567	102/308 (33%)
KIN3	NP_009410.1	STKc_Nek2	24..343	CDD:270857	102/309 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	180	1.000	Domainoid score	I711
eggNOG	1	0.900	-	-		E1_KOG0591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000168
OrthoInspector	1	1.000	-	-		oto100298
orthoMCL	1	0.900	-	-		OOG6_104455
Panther	1	1.100	-	-	LDO	PTHR43671
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R445
SonicParanoid	1	1.000	-	-		X4876
TreeFam	1	0.960	-	-
	11	10.800