Protein Alignment Nek2 and NEK3

DIOPT Version :9

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_001330383.1
• Gene: NEK3 / 832912
• AraportID: AT5G28290
• Length: 568
• Species: Arabidopsis thaliana
• Alignment Length: 652
• Identity: 170/652 - (26%)
• Similarity: 263/652 - (40%)
• Gaps: 158/652 - (24%)

  Fly    16 LQDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAKCDALVSEISVLRQLQHPNIVQ 80
            ::.||||..:|.||||:...||.|...:|:..|.:...........:...|:.::.::::|.||:
plant     1 MEHYEVLEQIGKGSFGSALLVRHKHEKKLYVLKKIRLARQTGRTRRSAHQEMELISKIRNPFIVE 65

  Fly    81 YYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQLCRALQVCHNKIPNG 145
            |....|.:.. .|.||:..|.|||:|:.:::|..  ..|.|..:.:.|.||..||:..|    ..
plant    66 YKDSWVEKGC-YVCIVIGYCKGGDMAEAIKKANG--VEFSEEKLCKWLVQLLMALEYLH----AS 123

  Fly   146 TILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRKYDRKSDVW 210
            .|||||:|.:||||....:.:|||||||::|..| ..|:|.||||.||.|||:....|..|||:|
plant   124 HILHRDVKCSNIFLTKDQDIRLGDFGLAKILTSD-DLASSVVGTPSYMCPELLADIPYGSKSDIW 187

  Fly   211 AVGCLVYEMCALRPPFRGRAFDQ--LSEKIAQGEFSRIPAIYSTDLQEIIAFMLAVDHEQRPGIE 273
            ::||.:|||.||:|.|  :|||.  |..:|.:...:.:||.|||..:.::..||..:.|.||...
plant   188 SLGCCMYEMTALKPAF--KAFDMQGLINRINRSIVAPLPAQYSTAFRSLVKSMLRKNPELRPSAS 250

  Fly   274 VIIRHPLVVRNISELDGKFPILVDSGEDFYTLPSGARLFEDEEEDGVHPELSSTMFTEQYSFNEG 338
            .::|.||:...:.::     :|..|..:..||||.:
plant   251 DLLRQPLLQPYVQKV-----LLKLSFREHDTLPSES----------------------------- 281

  Fly   339 YGQRRLSVTGVFTPDLRSELFYSAKRKIFPAKKLQLSDPSLYESIRREERAEERQVELAEERRRK 403
              :||.|              |..:||....|.:... ||.:...:.:..:..:.|.....|.|.
plant   282 --ERRSS--------------YPQQRKRTSGKSVSFG-PSRFGVDQEDSVSSVKPVHTYLHRHRP 329

  Fly   404 KDQEQQKRDQELLKEAPSSPRALTQNIFDEVLKTRLHAIRAQESLLQQKLEELQTREQELQLAEQ 468
            .|                    |:.|....|:..|    .|..|::....:.:..|..
plant   330 VD--------------------LSANDTSRVVVRR----PAVSSVVSNSSKYVPVRSN------- 363

  Fly   469 RVQTLERQMQEK---LLQQEKHTCSCRQPIAPPIPPRKPAKSHHDDTYCTIELNETSPTVAKLNL 530
                     |.|   ||:....|.....||:     :||||...|..|        .|.:..|:.
plant   364 ---------QPKSGGLLKPAVVTRRASLPIS-----QKPAKGTKDSLY--------HPNIGILHQ 406

  Fly   531 ATLPAPKSLNTLRKVTFKSPQ----KFVTYGIENMP-PPAVKP-------AVNPPPTGVPMQMSV 583
            ...|         .|:..||:    ||.....|.|| .|.|:.       :.:|||. .|:..|:
plant   407 LNSP---------DVSVNSPRIDRIKFPLASYEEMPFIPVVRKKKGSSRGSYSPPPE-PPLDCSI 461

  Fly   584 SSNDSGDSQASSTRRKSILSLFGLSRGSKATSKSLPSVNQVAQAAATRVQRPPLAVKPPITQEQP 648
            :.    |.......|::...|...:..:.|:|:        |.:.|:|.||     ..|.:..|.
plant   462 TK----DKFTLEPERETKSDLSDQNATAGASSR--------ASSGASRRQR-----FDPSSYRQR 509

  Fly   649 AE 650
            ||
plant   510 AE 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	98/264 (37%)
		S_TKc	19..281	CDD:214567	98/263 (37%)
NEK3	NP_001330383.1	STKc_Nek	3..258	CDD:270855	98/264 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	173	1.000	Inparanoid score	I1512
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000168
OrthoInspector	1	1.000	-	-		mtm947
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960