Protein Alignment Nek2 and NEK2

DIOPT Version :10

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_187132.1
• Gene: NEK2 / 819641
• AraportID: AT3G04810
• Length: 606
• Species: Arabidopsis thaliana
• Alignment Length: 603
• Identity: 164/603 - (27%)
• Similarity: 254/603 - (42%)
• Gaps: 148/603 - (24%)

  Fly    16 LQDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAKCDALVSEISVLRQLQHPNIVQ 80
            :::||||..:|.||||:...||.|...:|:..|.:...........:...|:.::.::.:|.||:
plant     1 MENYEVLEQIGKGSFGSALLVRHKHEKKLYVLKKIRLARQTGRTRRSAHQEMELISKIHNPFIVE 65

  Fly    81 YYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQLCRALQVCHNKIPNG 145
            |....|.:.. .|.|::..|.|||:|:.:::...  ..|.|..:.:.|.|:..||:..|    ..
plant    66 YKDSWVEKGC-YVCIIIGYCKGGDMAEAIKKTNG--VHFTEEKLCKWLVQILLALEYLH----AN 123

  Fly   146 TILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRKYDRKSDVW 210
            .|||||:|.:||||....:.:|||||||::|..| ..|:|.||||.||.|||:....|..|||:|
plant   124 HILHRDVKCSNIFLTKDQDIRLGDFGLAKVLTSD-DLASSVVGTPSYMCPELLADIPYGSKSDIW 187

  Fly   211 AVGCLVYEMCALRPPFRGRAFDQLSEKIAQGEFSRI--------PAIYSTDLQEIIAFMLAVDHE 267
            ::||.:|||.|::|.|  :|||.      ||..:||        ||.||...:.::..||..:.|
plant   188 SLGCCMYEMTAMKPAF--KAFDM------QGLINRINRSIVPPLPAQYSAAFRGLVKSMLRKNPE 244

  Fly   268 QRPGIEVIIRHPLVVRNISELDGKFPILVDSGEDFYTLPSGARLFEDEEEDGVHPELSSTMFTEQ 332
            .||....::|.||:...|.::..|   :.|.|.:  .||:            ..||..|   ..:
plant   245 LRPSAAELLRQPLLQPYIQKIHLK---VNDPGSN--VLPA------------QWPESES---ARR 289

  Fly   333 YSFNEGYGQRRLSVTGVFTPDLRSELFYSAKRKIFPAKKLQLSDPSLY--------ESIRREERA 389
            .||.|   |||.                       ||.|.....||.:        .||::...|
plant   290 NSFPE---QRRR-----------------------PAGKSHSFGPSRFRGNLEDSVSSIKKTVPA 328

  Fly   390 ---EERQVELAEERRRKKDQEQQKRDQELLKEAPSSPRALTQNIFDEVLKTRLHAIRAQESLLQQ 451
               .||||:|:.:  ...|....:|..|..|.:...|                  :||..|.::.
plant   329 YLNRERQVDLSTD--ASGDGTVVRRTSEASKSSRYVP------------------VRASASPVRP 373

  Fly   452 KLEELQTREQ--ELQLAEQRVQTLERQMQEKLLQQEKHTCSCRQPIAPPIPPRKPAKSHHDDTYC 514
            :    |.|..  :|.::.|             |:..|.....|:...|  ..|||||...|..|.
plant   374 R----QPRSDLGQLPVSSQ-------------LKNRKPAALIRRASMP--SSRKPAKEIKDSLYI 419

  Fly   515 --TIELNE-TSPTVAKLNLATLPAPKSLNTLRKVTFKSPQKFVTYGIENMPP--------PAVKP 568
              |..|:: .||.|      ::.||:    :.|:.|    ...:|..|...|        .:.:.
plant   420 SKTSFLHQINSPDV------SMNAPR----IDKIEF----PLASYEEEPFVPVVRGKKKKASSRG 470

  Fly   569 AVNPPPTGVPMQMSVSSN 586
            :.:|||. .|:..|::.:
plant   471 SYSPPPE-PPLDCSITKD 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	95/270 (35%)
NEK2	NP_187132.1	STKc_Nek	3..258	CDD:270855	95/270 (35%)