Protein Alignment Nek2 and AT2G32850

DIOPT Version :10

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_850199.1
• Gene: AT2G32850 / 817846
• AraportID: AT2G32850
• Length: 670
• Species: Arabidopsis thaliana
• Alignment Length: 774
• Identity: 173/774 - (22%)
• Similarity: 296/774 - (38%)
• Gaps: 187/774 - (24%)

  Fly     4 EESAGMD--FSQKTLQDYEVLAVMGNGSFGTCYKVRD-KSTGELFAWKGMNYDELDEAKCDALVS 65
            :|.||::  |.:......:|..|:..|.|.:.|..:| ....:.:|.|.|..:  ||...:.::.
plant    10 KEPAGLEGRFLEIGNLKVQVRNVIAEGGFSSVYLAQDVNHASKQYALKHMICN--DEESLELVMK 72

  Fly    66 EISVLRQLQ-HPNIVQYYHHLV---NREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWR 126
            |||||:.|: |||:|..|.|.:   .|..|...:.|:.| |..|..:::...:  ..|||.....
plant    73 EISVLKSLKGHPNVVTLYAHGILDMGRNKKEALLAMDFC-GKSLVDVLENRGA--GYFEEKQALT 134

  Fly   127 VLFQLCRALQVCHNKIPNGTILHRDIKPANIFLDAAGNAKLGDFGLA----RMLRRDQSFAASFV 187
            :...:|.|:...|.:.|.  |.|||:|..|:.|.:.|..||.|||..    ::..|     |..:
plant   135 IFRDVCNAVFAMHCQSPR--IAHRDLKAENLLLSSDGQWKLCDFGSVSTNHKIFER-----AEEM 192

  Fly   188 G----------TPHYMSPE---LVKGRKYDRKSDVWAVGCLVYEMCALRPPFRGRAFDQLSE-KI 238
            |          ||.|.:||   |.:......|.|:||:|||::.:|..:     .|||..|: :|
plant   193 GIEEDNIRKYTTPTYRAPEMWDLFRREMISEKVDIWALGCLLFRICYFK-----NAFDGESKLQI 252

  Fly   239 AQGEFSRIPAI--YSTDLQEIIAFMLAVDHEQRPGIEVI---IRHPLVVRNISELDGKFPILVDS 298
            ..|.: |||..  ||..:.::|..||....::||.|..|   :...|.......|..:.|.:..:
plant   253 LNGNY-RIPESPKYSVFITDLIKEMLQASPDERPDITQIWFRVNEQLPANLQKSLPDRPPEMQST 316

  Fly   299 G-----EDFYTLPSGARLF-------EDEEEDGVHPELSSTMFTEQYSFNEGYGQRRLSVTGVFT 351
            |     ....|.||.|...       ...|.|...| |.:...|:.            :.|.|.:
plant   317 GVHDGSSKSATKPSPAPRRSPPPPPPSSGESDSGGP-LGAFWATQH------------AKTSVVS 368

  Fly   352 PDLRSELFYSAKRKIFPAKKLQLSDPSLYESIRREERAEERQVELAEERR---RKKDQE---QQK 410
            .|          .|..|......|:.|..|.:|.:....::...:..|.|   |.||.|   .||
plant   369 ED----------NKNMPKFDEPNSNTSKSERVRVDSHQPKKPSPVRGEARGIQRNKDLETTISQK 423

  Fly   411 RDQELLKEAPSSPRALTQNIFDEVLKT-----------------RLHAIRAQESLLQQKLEELQT 458
                  ...|::...:|:...|:...:                 :..|:.|:...|:.:|::.::
plant   424 ------NTTPAAANNMTRVSKDDAFNSFVADFDTTKFDNGNKPGKEEALEAEIQRLKDELKQTKS 482

  Fly   459 REQELQLAEQRVQTLERQMQEKLLQQEKHTCSCRQPIAPPIPPRKPAKSHHDDTYCTIELNETSP 523
            .:.|:....:::..:.|..::: ||..|.|.:.:.  |.|.|.|..::            |:.||
plant   483 EKAEITAKFEKLSAICRSQRQE-LQDLKQTLASKS--ASPSPSRDSSQ------------NQPSP 532

  Fly   524 TVAKLNLATLPAPKSLNTLRKVTFKSPQKFVTYGIENMPPPAVKPAVNPPPTGVPMQMSVSSNDS 588
                 .:.::.:..|.:.:....::..|....:                         |..|:|:
plant   533 -----GMHSMSSTPSRDKMEGTMWELQQDRSNW-------------------------STGSSDT 567

  Fly   589 GDSQASSTRRKSILSLFGLSRGSKAT-SKSLPSVNQVAQAAATRVQRPPLAVKPPITQEQPAEVP 652
            ...|..|...|.::.  ..|:|:..| ::|:.:.::.|.||.|:...|
plant   568 NSWQPFSDEAKPVME--SASKGNNNTINQSVRTRSKPASAAGTQGFEP----------------- 613

  Fly   653 PVANLWTKEQKKQAFELLAAMNAAEREASG-GGVVGSGPGGARRQHLRQSVRERNSTLQ 710
                 |..|  .::|. .||.:||...||| ...:|||...::| :....:||...|.|
plant   614 -----WGFE--TESFR-AAATSAAATSASGTQRSMGSGNSTSQR-YGNSKMRENQKTAQ 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	84/290 (29%)
AT2G32850	NP_850199.1	STKc_GAK_like	26..299	CDD:270887	84/290 (29%)