DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nek2 and Nek6

DIOPT Version :9

Sequence 1:NP_572415.1 Gene:Nek2 / 31696 FlyBaseID:FBgn0029970 Length:735 Species:Drosophila melanogaster
Sequence 2:XP_006498272.1 Gene:Nek6 / 59126 MGIID:1891638 Length:358 Species:Mus musculus


Alignment Length:265 Identity:99/265 - (37%)
Similarity:154/265 - (58%) Gaps:16/265 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 TLQDYEVLAVMGNGSFGTCYK---VRDKSTGELFAWKGMNYDELDEAKC-DALVSEISVLRQLQH 75
            :|.|:::...:|.|.|...||   :.|:.|   .|.|.:...|:.:||. ...|.||.:|:||.|
Mouse    86 SLADFQIEKKIGRGQFSEVYKATCLLDRKT---VALKKVQIFEMMDAKARQDCVKEIGLLKQLNH 147

  Fly    76 PNIVQYYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQLCRALQVCHN 140
            |||::|....:  |...:.||:|....|||:|:::..:.|::...|..:|:...|||.|::..|:
Mouse   148 PNIIKYLDSFI--EDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 210

  Fly   141 KIPNGTILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRKYDR 205
            :    .::||||||||:|:.|.|..||||.||.|....:.:.|.|.||||:|||||.:....|:.
Mouse   211 R----RVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNF 271

  Fly   206 KSDVWAVGCLVYEMCALRPPFRGRAFD--QLSEKIAQGEFSRIPA-IYSTDLQEIIAFMLAVDHE 267
            |||:|::|||:|||.||:.||.|...:  .|.:||.|.::..:|. .||..|:|:::..:..|.:
Mouse   272 KSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPD 336

  Fly   268 QRPGI 272
            .||.|
Mouse   337 HRPDI 341

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nek2NP_572415.1 STKc_Nek2 18..281 CDD:270857 98/262 (37%)
S_TKc 19..281 CDD:214567 97/261 (37%)
Nek6XP_006498272.1 STKc_Nek6 87..354 CDD:270865 99/264 (38%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0591
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000168
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R445
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.840

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