Protein Alignment Nek2 and Nek7

DIOPT Version :9

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_067618.1
• Gene: Nek7 / 59125
• MGIID: 1890645
• Length: 302
• Species: Mus musculus
• Alignment Length: 292
• Identity: 102/292 - (34%)
• Similarity: 159/292 - (54%)
• Gaps: 26/292 - (8%)

  Fly     4 EESAGM----------------DFSQKTLQDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNY 52
            |:|.||                |....||.::.:...:|.|.|...|:......|...|.|.:..
Mouse     3 EQSQGMQGPPVTQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQI 67

  Fly    53 DELDEAKCDA-LVSEISVLRQLQHPNIVQYYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQR 116
            .:|.:||..| .:.||.:|:||.|||:::||...:  |...:.||:|....|||:::::..:.|:
Mouse    68 FDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFI--EDNELNIVLELADAGDLSRMIKHFKKQK 130

  Fly   117 QRFEEPYIWRVLFQLCRALQVCHNKIPNGTILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQS 181
            :...|..:|:...|||.||...|::    .::||||||||:|:.|.|..||||.||.|......:
Mouse   131 RLIPERTVWKYFVQLCSALDHMHSR----RVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTT 191

  Fly   182 FAASFVGTPHYMSPELVKGRKYDRKSDVWAVGCLVYEMCALRPPFRGRAFD--QLSEKIAQGEFS 244
            .|.|.||||:|||||.:....|:.|||:|::|||:|||.||:.||.|...:  .|.:||.|.::.
Mouse   192 AAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYP 256

  Fly   245 RIPA-IYSTDLQEIIAFMLAVDHEQRPGIEVI 275
            .:|: .||.:|::::...:..|.|:||.|..:
Mouse   257 PLPSDHYSEELRQLVNICINPDPEKRPDIAYV 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	95/262 (36%)
		S_TKc	19..281	CDD:214567	95/261 (36%)
Nek7	NP_067618.1	NTE motif. /evidence=ECO:0000250	20..33		3/12 (25%)
		STKc_Nek6_7	33..294	CDD:270863	95/262 (36%)
		S_TKc	34..286	CDD:214567	94/257 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000168
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R445
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840