Protein Alignment Nek2 and nek2

DIOPT Version :10

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_957344.1
• Gene: nek2 / 394025
• ZFINID: ZDB-GENE-040426-752
• Length: 440
• Species: Danio rerio
• Alignment Length: 496
• Identity: 182/496 - (36%)
• Similarity: 269/496 - (54%)
• Gaps: 93/496 - (18%)

  Fly    17 QDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAKCDALVSEISVLRQLQHPNIVQY 81
            :|||||..:|.||:|.|.|::.||.|::..||.::|..:.|.:...||||:::||:|:|||||:|
Zfish     6 EDYEVLLTIGCGSYGKCQKIKRKSDGKILVWKVLDYGTMAEGEKQMLVSEVNLLRELKHPNIVRY 70

  Fly    82 YHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQLCRALQVCHNKIPNG- 145
            :..:::|...::|||||.|.|||||.::.|:...::..||.:|.||:.||..||:.||.: .||
Zfish    71 HDRIIDRTNTTLYIVMEYCEGGDLASLINRSIKDKRYLEEEFILRVMAQLSLALKECHGR-SNGS 134

  Fly   146 -TILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRKYDRKSDV 209
             |:||||:|||||||||..|.|||||||||:|..|.|||.:|||||:|||||.:....|:.|||:
Zfish   135 STVLHRDLKPANIFLDAKQNVKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDI 199

  Fly   210 WAVGCLVYEMCALRPPFRGRAFDQLSEKIAQGEFSRIPAIYSTDLQEIIAFMLAVDHEQRPGIEV 274
            |::|||:||:|||.|||......:|:.||.:|.|.|||..||.:|..:::.||.:....||.:|.
Zfish   200 WSLGCLLYELCALSPPFTAYNQTELARKIREGRFRRIPYRYSDELNTLLSKMLNLKDYLRPSVES 264

  Fly   275 IIRHPLVVRNISELDGKFPILVDSGEDFYTLPSGARLFEDEEEDGVHPELSSTMFTEQYSFNEGY 339
            |:::.|:...:: |:.|            .|....|...||.|...|||
Zfish   265 ILQNGLISGYVA-LEQK------------RLQEKQRRRSDEAEQPKHPE---------------- 300

  Fly   340 GQRRLSVTGVFTPDLRSELFYSAKRKIFPAKKLQLSDPSLYESIRREERAEERQVELAEERRRKK 404
                       :| |.:||  ..|.:|...::..|.:        ||:|.|:|:.||..  |.::
Zfish   301 -----------SP-LLAEL--RLKEQILREREQALKE--------REQRLEQREQELCV--REQQ 341

  Fly   405 DQEQQKRDQELLK--EAPSSPRAL-------TQNIFDEVL---KTRLH-----------AIRAQE 446
            ..|:..|.:.:||  ......|||       |:|  :|.:   |.|:|           .::.||
Zfish   342 TNEKLVRAESMLKAFNLIRQQRALSLLSASDTEN--EENISPGKKRVHFAGDGKENGRLIMKPQE 404

  Fly   447 SLLQQKLEELQTREQELQLAEQRVQTLERQMQEKLLQQEKH 487
            .:|          |:..||..:|:|||..  :||::...||
Zfish   405 HIL----------EKRHQLMNKRIQTLGE--EEKMIHSPKH 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	129/264 (49%)
nek2	NP_957344.1	STKc_Nek2	7..271	CDD:270857	129/264 (49%)