Protein Alignment Nek2 and Nek7

DIOPT Version :10

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_001101816.1
• Gene: Nek7 / 360850
• RGDID: 1311160
• Length: 302
• Species: Rattus norvegicus
• Alignment Length: 270
• Identity: 98/270 - (36%)
• Similarity: 154/270 - (57%)
• Gaps: 10/270 - (3%)

  Fly    10 DFSQKTLQDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAKCDA-LVSEISVLRQL 73
            |....||.::.:...:|.|.|...|:......|...|.|.:...:|.:||..| .:.||.:|:||
  Rat    25 DMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQL 89

  Fly    74 QHPNIVQYYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQLCRALQVC 138
            .|||:::||...:  |...:.||:|....|||:::::..:.|::...|..:|:...|||.||...
  Rat    90 NHPNVIKYYASFI--EDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHM 152

  Fly   139 HNKIPNGTILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRKY 203
            |::    .::||||||||:|:.|.|..||||.||.|......:.|.|.||||:|||||.:....|
  Rat   153 HSR----RVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGY 213

  Fly   204 DRKSDVWAVGCLVYEMCALRPPFRGRAFD--QLSEKIAQGEFSRIPA-IYSTDLQEIIAFMLAVD 265
            :.|||:|::|||:|||.||:.||.|...:  .|.:||.|.::..:|: .||.:|::::...:..|
  Rat   214 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPD 278

  Fly   266 HEQRPGIEVI 275
            .|:||.|..:
  Rat   279 PEKRPDIAYV 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	95/262 (36%)
Nek7	NP_001101816.1	NTE motif. /evidence=ECO:0000250|UniProtKB:Q8TDX7	20..33		3/7 (43%)
		STKc_Nek6_7	33..294	CDD:270863	95/262 (36%)