Protein Alignment Nek2 and Nek6

DIOPT Version :10

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_891998.1
• Gene: Nek6 / 360161
• RGDID: 727779
• Length: 313
• Species: Rattus norvegicus
• Alignment Length: 268
• Identity: 100/268 - (37%)
• Similarity: 155/268 - (57%)
• Gaps: 16/268 - (5%)

  Fly    15 TLQDYEVLAVMGNGSFGTCYK---VRDKSTGELFAWKGMNYDELDEAKC-DALVSEISVLRQLQH 75
            :|.|:::...:|.|.|...||   :.|:.|   .|.|.:...|:.:||. ...|.||.:|:||.|
  Rat    41 SLADFQIEKKIGRGQFSEVYKATCLLDRKT---VALKKVQIFEMMDAKARQDCVKEIGLLKQLNH 102

  Fly    76 PNIVQYYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQLCRALQVCHN 140
            |||::|....:  |...:.||:|....|||:|:::..:.|::...|..:|:...|||.|::..|:
  Rat   103 PNIIKYLDSFI--EDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHS 165

  Fly   141 KIPNGTILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRKYDR 205
            :    .::||||||||:|:.|.|..||||.||.|....:.:.|.|.||||:|||||.:....|:.
  Rat   166 R----RVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNF 226

  Fly   206 KSDVWAVGCLVYEMCALRPPFRGRAFD--QLSEKIAQGEFSRIPA-IYSTDLQEIIAFMLAVDHE 267
            |||:|::|||:|||.||:.||.|...:  .|.:||.|.::..:|. .||..|:|:::..:..|..
  Rat   227 KSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPN 291

  Fly   268 QRPGIEVI 275
            .||.||.:
  Rat   292 HRPDIEYV 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	99/265 (37%)
Nek6	NP_891998.1	Interaction with ARHGAP33, ANKRA2, CDC42, PRDX3, RAD26L, RBBP6, RPS7 and TRIP4. /evidence=ECO:0000250	1..44		1/2 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31
		STKc_Nek6_7	44..305	CDD:270863	99/265 (37%)
		Interaction with APBB1. /evidence=ECO:0000250	267..270		0/2 (0%)