DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nek2 and CG7420

DIOPT Version :9

Sequence 1:	NP_572415.1	Gene:	Nek2 / 31696	FlyBaseID:	FBgn0029970	Length:	735	Species:	Drosophila melanogaster
Sequence 2:	NP_001259871.1	Gene:	CG7420 / 33332	FlyBaseID:	FBgn0031344	Length:	388	Species:	Drosophila melanogaster

Alignment Length:	161	Identity:	37/161 - (22%)
Similarity:	61/161 - (37%)	Gaps:	45/161 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 ELD-EAKCDALVSEISVLRQLQHPNIVQYYHHLVNREAKSVYIVMECC-----AGGDLAQIV--- 109
            ||| .|.|....:.:.:  |:.:||.::    :|:..:...::|::|.     .||...:|:
  Fly   182 ELDITATCLHRCNTVKI--QVHNPNELR----IVSISSGQNHMVLKCADLSETGGGSTKRILTLG 240

  Fly   110 --QRARSQRQRFEEPYIWRVLFQLCRALQV--CHNK--IPNGTILHRDIKPANIFLDAAGNAKLG 168
              :..:|...:|||.         .|.|.|  .||.  :.|..||   :...|.:    |...:|
  Fly   241 DNKFGQSNAFQFEED---------VRQLAVGWTHNAAVLKNNEIL---VWGRNCY----GQLGMG 289

  Fly   169 DFG--------LARMLRRDQSFAASFVGTPH 191
            .|.        |...|..||..|...:|..|
  Fly   290 SFSEQQAIPTPLRLKLPEDQGPARIHMGAEH 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	37/161 (23%)
Nek2	NP_572415.1	S_TKc	19..281	CDD:214567	37/161 (23%)
CG7420	NP_001259871.1	RCC1	2..52	CDD:278826
		RCC1	55..107	CDD:278826
		RCC1	112..161	CDD:278826
		RCC1_2	256..285	CDD:290274	9/35 (26%)
		RCC1	274..320	CDD:278826	12/52 (23%)
		RCC1	328..>348	CDD:278826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.010