Protein Alignment Nek2 and Nek8

DIOPT Version :10

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_001099274.1
• Gene: Nek8 / 287473
• RGDID: 1306897
• Length: 698
• Species: Rattus norvegicus
• Alignment Length: 269
• Identity: 94/269 - (34%)
• Similarity: 156/269 - (57%)
• Gaps: 10/269 - (3%)

  Fly    16 LQDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAKCDALVSEISVLRQLQHPNIVQ 80
            ::.||.:.|:|.|:||..:....|:..:|...|.:..:::.:.:..|..:|..||:.|.|||:::
  Rat     1 MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIE 65

  Fly    81 YYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQLCRALQVCHNKIPNG 145
            ||.:.:  |.|::.|.||...||.||:.:|:..:  ...||..|.....|:..||...|..:
  Rat    66 YYENFL--EDKALMIAMEYAPGGTLAEFIQKRCN--SLLEEETILHFFVQILLALHHVHTHL--- 123

  Fly   146 TILHRDIKPANIFLDAAGN-AKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRKYDRKSDV 209
             |||||:|..||.||.... .|:||||::::| ..:|.|.:.||||.|:||||.:|:.|::|||:
  Rat   124 -ILHRDLKTQNILLDKHRMVVKIGDFGISKIL-SSKSKAYTVVGTPCYISPELCEGKPYNQKSDI 186

  Fly   210 WAVGCLVYEMCALRPPFRGRAFDQLSEKIAQGEFSRIPAIYSTDLQEIIAFMLAVDHEQRPGIEV 274
            ||:||::||:.:|:..|.......|..||..|.|:.|...||.:|::::..:|:::..|||.:..
  Rat   187 WALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSH 251

  Fly   275 IIRHPLVVR 283
            |:..||.:|
  Rat   252 IMAQPLCIR 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	92/263 (35%)
Nek8	NP_001099274.1	STKc_Nek8	3..258	CDD:270859	92/263 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..307
		ATS1	401..>690	CDD:444065
		RCC1 1	415..466
		RCC1 2	467..518
		RCC1 3	520..571
		RCC1 4	585..636
		RCC1 5	638..689