Protein Alignment Nek2 and nekl-2

DIOPT Version :10

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_491914.1
• Gene: nekl-2 / 191199
• WormBaseID: WBGene00022631
• Length: 357
• Species: Caenorhabditis elegans
• Alignment Length: 275
• Identity: 84/275 - (30%)
• Similarity: 155/275 - (56%)
• Gaps: 15/275 - (5%)

  Fly    16 LQDYEVLAVMGNGSFGTCYKVRDK--STGELFAWKGMNYDELDEAKCDALVSEISVLRQLQHPNI 78
            :.:||.:.|:|.|:||.|:..|.|  ::.:....|.:|...:.|.:.:::.||:::|:::|||.|
 Worm     1 MDNYEKVRVVGRGAFGVCWLCRGKNDASHQKVIIKLINTHGMTEKEENSIQSEVNLLKKVQHPLI 65

  Fly    79 VQYYHHLVNREAKSVYIVMECCAGGDLAQIV--QRA---RSQRQRFEEPYIWRVLFQLCRALQVC 138
            :.|....:  ....:.|||:...||.|.:::  |||   .:.|:.|.|..:.....|:..||...
 Worm    66 IGYIDSFI--MDNQLGIVMQYAEGGTLERLINDQRAIKDSNMREYFPEKTVLDYFTQILIALNHM 128

  Fly   139 HNKIPNGTILHRDIKPANIFLDAAGNA-KLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRK 202
            |.|    .|:|||:||.||.::..... ||.|||:::.| ..:|.|::.:|||:|:|||:.:.|.
 Worm   129 HQK----NIVHRDLKPQNILMNRRKTVLKLSDFGISKEL-GTKSAASTVIGTPNYLSPEICESRP 188

  Fly   203 YDRKSDVWAVGCLVYEMCALRPPFRGRAFDQLSEKIAQGEFSRIPAIYSTDLQEIIAFMLAVDHE 267
            |::|||:|::||::||:..|...|.|.....:..||.:.:.:.:....|.|::.::..:|....:
 Worm   189 YNQKSDMWSLGCVLYELLQLERAFDGENLPAIVMKITRSKQNPLGDHVSNDVKMLVENLLKTHTD 253

  Fly   268 QRPGIEVIIRHPLVV 282
            :||.:..::..|||:
 Worm   254 KRPDVSQLLSDPLVL 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	82/270 (30%)
nekl-2	NP_491914.1	STKc_Nek	3..267	CDD:270855	82/270 (30%)