Protein Alignment Nek2 and mekk-3

DIOPT Version :9

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_492629.1
• Gene: mekk-3 / 172850
• WormBaseID: WBGene00013694
• Length: 430
• Species: Caenorhabditis elegans
• Alignment Length: 325
• Identity: 77/325 - (23%)
• Similarity: 134/325 - (41%)
• Gaps: 82/325 - (25%)

  Fly    19 YEVLAVMGNGSFGTCYKVRDKSTG----ELFAWKGMNYDELDEAKCDALVSEISVLRQLQHPNIV 79
            |.:..::|.|:.|:.|....|..|    ::.:..|.:..:  ||       ::..||.|:|..||
 Worm   157 YSLGKLIGRGTLGSVYLAEGKKGGTYAVKIISKHGRHLPQ--EA-------DVEYLRMLRHVRIV 212

  Fly    80 QYYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQLCRALQVCHNKIPN 144
            :|.:.:...::..::|:||....|.|.:.:.|.........:.|..::|    ..|:..|:|
 Worm   213 EYLYIIEPSKSNDIHILMEYMHTGSLQEYIARTGPLHHELVKAYAKQIL----EGLEFLHSK--- 270

  Fly   145 GTILHRDIKPANIFLDAAGN---AKLGDFGLARM--LRRDQSFAASFVGTPHYMSPELVKGRKYD 204
             .|:|:|:||||:.|.....   .|:.|||.:|.  |:|::.....  .||.|..|.:..||...
 Worm   271 -NIIHQDLKPANLLLKNTHRERLIKIADFGSSRFSSLKREREGQQG--RTPKYTDPGVSLGRHVS 332

  Fly   205 -RKSDVWAVGCLVYEMCALRPPFR---------GRAFDQ------LSEKIAQGEFSRIPAIYSTD 253
             |:||:|::|.::.||.....|:.         .|..|:      .||||.:            :
 Worm   333 GRRSDIWSLGVIIIEMYTGVYPWSIDGEHPITVPRILDENPPNFTTSEKIDE------------N 385

  Fly   254 LQEIIAFMLAVDHEQRPGIEVIIRHPLVVRNISELDGKFPILVDSGEDFYTLPSGARLFEDEEED 318
            |.::...||. ...:||....::              :.|||.:|.|:           |||:.|
 Worm   386 LIKMAKLMLQ-SVAKRPYASTLL--------------ELPILQESSEN-----------EDEDSD 424

  Fly   319  318
             Worm   425  424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	68/286 (24%)
		S_TKc	19..281	CDD:214567	68/286 (24%)
mekk-3	NP_492629.1	S_TKc	157..412	CDD:214567	69/300 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157637
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930