Protein Alignment Nek2 and LOC100486333

DIOPT Version :10

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: XP_002936837.2
• Gene: LOC100486333 / 100486333
• XenbaseID: XB-GENE-29078291
• Length: 494
• Species: Xenopus tropicalis
• Alignment Length: 481
• Identity: 127/481 - (26%)
• Similarity: 223/481 - (46%)
• Gaps: 60/481 - (12%)

  Fly    16 LQDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAK-CDALVSEISVLRQLQHPNIV 79
            ::.||.:..:|.|:....:.:|:|.|.:.:|.|.:..||....: .::::.|.::|.:|.||::|
 Frog     1 MEKYEKILKIGRGATAEVFLMRNKETKKNYAVKKIKIDESKRLRNKESILQEATILGKLVHPHVV 65

  Fly    80 QYYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQR----FEEPYIWRVLFQLCRALQVCHN 140
            ..:..:.:.|.:.::||.:.|.||.|...:      :||    |.|..|.....||..|:|..|:
 Frog    66 ACHECICDEEDEHIFIVQDYCDGGTLDDHI------KQRNGALFPEDTIMDWFIQLTMAVQYIHS 124

  Fly   141 KIPNGTILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRKYDR 205
            .    .|||||||.:|:||...|..:|||||::::|......|::.||||:|:||||.:...|..
 Frog   125 M----KILHRDIKTSNVFLTKKGMVRLGDFGISKVLSSTMDMASTCVGTPYYLSPELCQDIPYSS 185

  Fly   206 KSDVWAVGCLVYEMCALRPPFRGRAFDQLSEKIAQGEFSRIPAIYSTDLQEIIAFMLAVDHEQRP 270
            |||:||:|||:||||||:|.|.......|..||.:||:..|...||.||.:::..:|....|.||
 Frog   186 KSDIWALGCLLYEMCALQPAFNAANLISLFFKIVKGEYPPISDCYSIDLHKLVKTILDKCPESRP 250

  Fly   271 GIEVIIRHPLVVRNISELDGKFPILVDSGEDFYTLPSGARLFED--EEEDGVHPE--LSSTMFTE 331
            ....|:       |:|.:..:..:.:...|        ::|:..  .:::...|:  .|.|....
 Frog   251 SASCIL-------NLSFVQEQLKLFIQKHE--------SQLYRQTASKKENTSPQENRSKTSVGH 300

  Fly   332 QYSFNEGYGQRRLSVTGVFTPDLRSELFYSAKRKIFPAKKL-QLSDPSLYESIRREERAEERQVE 395
            ..:..:.: :.:.:..|.:.||:       .|.:::..::| ...|.|.|.    |:..:...|.
 Frog   301 HDTAKDNF-RPKSAPPGPYKPDV-------TKCELWDQEELSSTGDKSEYS----EDFDDNESVS 353

  Fly   396 LAEERRRKKD----------QEQQKRDQELLKEAPSSPRALTQNIFDEVLKTRLHAIRAQESLLQ 450
            ..||....::          :|....|.|...|.|.....:..|..:.|:.   ||..|.|....
 Frog   354 SVEENLEGENGTPCENEDIPEEIDLVDDEGESEYPDDFEEVEGNTLEMVVS---HARSAMEVEAD 415

  Fly   451 QKLEELQTREQELQLAEQRVQTLERQ 476
            .:..:....:|:.|.....::|:.:|
 Frog   416 NETFQDDNGDQDNQSLSATLKTIRQQ 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	93/267 (35%)
LOC100486333	XP_002936837.2	STKc_Nek	3..261	CDD:270855	95/274 (35%)