Protein Alignment Nek2 and nek9

DIOPT Version :10

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_001427666.1
• Gene: nek9 / 100334361
• ZFINID: ZDB-GENE-160718-1
• Length: 921
• Species: Danio rerio
• Alignment Length: 655
• Identity: 166/655 - (25%)
• Similarity: 265/655 - (40%)
• Gaps: 168/655 - (25%)

  Fly     1 MSGEESA--GMDFSQKTLQDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAKCDAL 63
            :||..:|  |:...:..|. |..:.|:|.|:||.....|......|..||.::.:.|.:.|...:
Zfish    22 VSGRSAASGGLSGEEDKLH-YIPIRVLGKGAFGEATLYRRTEDNSLVVWKEIDLNCLSDKKRRDV 85

  Fly    64 VSEISVLRQLQHPNIVQYYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVL 128
            ::|||:|..|.|.||:.|::|.:::  .::.|.:|.|.||:|...:.:.:....: ||..:| .|
Zfish    86 MNEISILSILHHNNIIAYFNHFLDK--NTLLIELEYCNGGNLYDKINQQKGALFK-EEVVVW-YL 146

  Fly   129 FQLCRALQVCHNKIPNGTILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAASFVGTPHYM 193
            :|:..|  |.|  |....|||||||..||||......||||:|||:.|....|.|.:.||||:||
Zfish   147 YQIAAA--VAH--IHKAGILHRDIKTLNIFLTKTNLIKLGDYGLAKKLDSQYSMAETCVGTPYYM 207

  Fly   194 SPELVKGRKYDRKSDVWAVGCLVYEMCALRPPFRGRAFD-----QLSEKIAQGEFS-RIPA-IYS 251
            ||||.:|.||:.|||:||:||:::|:..|.     |.||     .|..||.||.:: .|.: :|:
Zfish   208 SPELCQGVKYNFKSDIWAMGCVLFELLTLT-----RTFDATNPLNLCVKIVQGNWTMEINSDVYT 267

  Fly   252 TDLQEIIAFMLAVDHEQRPGIEVIIRHPLVVRNISELDGKFPILVDSGEDFYTLPSGARLFEDEE 316
            ::|.:::...|..|.|:||..|.|:..|::..          :.|:..|....|.|..|
Zfish   268 SELIKLVYECLDQDPEKRPTAEQILEQPVISH----------VRVELEERVAALNSAIR------ 316

  Fly   317 EDGVHPELS----------STMFTEQYSFNEGYGQRRLSVTGVFTPDLRSELF------------ 359
                .|:||          :|...|.|.:.          .|.|||. :.::|
Zfish   317 ----KPKLSTVTETSVAVVTTRSREVYFWG----------GGKFTPQ-KLDMFKGGSSAQHVCAG 366

  Fly   360 ------YSAKRKIFP-------AK---KLQLSDPSLYESIRREERAEE---RQVELAEERRRKKD 405
                  .:.:::::.       ||   :|...|.:.|...||.||.:.   |||....:
Zfish   367 ETHFAVVTVEKELYTWASVQGGAKMVGQLGHGDQASYRQPRRVERLQGKAIRQVSCGAD------ 425

  Fly   406 QEQQKRDQELLKEAPSSPRALTQNIFDE----VLKTRLHAIRAQESLLQQKLEELQTREQELQLA 466
                                .|..:.||    :..:..:.....|:.|..::.|....|...:.|
Zfish   426 --------------------FTACVTDEDQIYMFGSDYYGCVGVENELGMEVLEPVLLEFFTERA 470

  Fly   467 EQRVQTLERQMQEKLLQQEKHT--C--------SCRQPIAPPIPPRKPAKSHHDDTYC----TIE 517
            .::|...:..:......:|.:.  |        .|....:.|:....|..:..|..||    |..
Zfish   471 VRQVSCGDNHVLALTQSRELYAWGCGEHGRLGLDCEDDFSSPMQVEVPQGAVIDSVYCGSDGTFF 535

  Fly   518 LNETSPTVA-------KLNL---------------------ATLPAPKSLNTLRKVTFKSPQKFV 554
            |.|:...:|       ||.|                     .||...|.|:.. |:.|.:|.|..
Zfish   536 LTESGKVLACGNNEFNKLGLNQGITGIKNHPGEGYQGIPYTTTLTLVKLLSRF-KIQFLAPGKTH 599

  Fly   555 TYGIE 559
            |..|:
Zfish   600 TAAID 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	99/269 (37%)
nek9	NP_001427666.1	None