Protein Alignment Nek2 and nek2

DIOPT Version :10

• Sequence 1: NP_572415.1
• Gene: Nek2 / 31696
• FlyBaseID: FBgn0029970
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_001164656.1
• Gene: nek2 / 100328980
• XenbaseID: XB-GENE-29077543
• Length: 442
• Species: Xenopus tropicalis
• Alignment Length: 489
• Identity: 183/489 - (37%)
• Similarity: 259/489 - (52%)
• Gaps: 77/489 - (15%)

  Fly    16 LQDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAKCDALVSEISVLRQLQHPNIVQ 80
            ::|||||..:|:||:|.|.|:|.:|.|:|..||.::|..:.||:...||||:::||:|:|||||:
 Frog     5 VEDYEVLYTIGSGSYGKCQKIRRRSDGKLLVWKELDYGTMTEAEKQMLVSEVNLLRELKHPNIVR 69

  Fly    81 YYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQLCRALQVCHNKIPNG 145
            ||..:::|...::|||||.|.|||||.::.:...:||..||.:|.|:..||..||:.||.:...|
 Frog    70 YYDRIIDRTNTTLYIVMEYCEGGDLASLIAKCTKERQYLEEDFILRIFSQLALALKDCHKRSDGG 134

  Fly   146 -TILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRKYDRKSDV 209
             |:||||:|||||||||..|.|||||||||:|..|.|||.:|||||:|||||.:....|:.|||:
 Frog   135 HTVLHRDLKPANIFLDAKNNVKLGDFGLARILHHDSSFAKTFVGTPYYMSPEQMNRMSYNEKSDI 199

  Fly   210 WAVGCLVYEMCALRPPFRGRAFDQLSEKIAQGEFSRIPAIYSTDLQEIIAFMLAVDHEQRPGIEV 274
            |::|||:||:|||.|||......:|:|||.:|.|.|||..||.:|.::|..||.:....||.||.
 Frog   200 WSLGCLLYELCALSPPFTAYNQKELAEKIREGRFRRIPYRYSEELNQVITNMLHLKDYLRPSIEE 264

  Fly   275 IIRHPLVVRNISELDGKFPILVDSGEDFYTLPSGARLFEDEEEDGVHPELSSTMFTEQYSFNEGY 339
            |::|.|:                           |.|..:|::.           ||:......
 Frog   265 ILQHHLL---------------------------AELVREEQKK-----------TEKKVLRAA- 290

  Fly   340 GQRRLSVTGVFTPDLRSELFYSAKRKIFPAKKLQLSDPSLYESIRREERAEERQVELAEERRRKK 404
            .|.|||:......:||           ...::|...:.:|.|   ||||.|:|:.||....|..:
 Frog   291 EQERLSMPDPVPSELR-----------LKEQQLHTRERALRE---REERLEQRERELCVRERMAE 341

  Fly   405 DQ----EQQKRDQELLKEA----------------PSSPRALTQNIFDEVLKTRLHAIRAQESLL 449
            |:    |...:...|:||.                .||.|:.....|....|......|.:|
 Frog   342 DKLARAETLVKSFNLMKEQHLFQAALENGKDAYVDSSSTRSRRHVHFGSNSKENSSTDRYRE--- 403

  Fly   450 QQKLEELQTREQELQLAEQRVQTLERQMQEKLLQ 483
            |:|..:||.|.|...:..:.:..|||..|.|..|
 Frog   404 QEKCSDLQKRLQAANIRAKALSELERNYQLKSRQ 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	135/263 (51%)
nek2	NP_001164656.1	STKc_Nek2	7..271	CDD:270857	135/263 (51%)