DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10932 and acat1

DIOPT Version :9

Sequence 1:	NP_001284987.1	Gene:	CG10932 / 31695	FlyBaseID:	FBgn0029969	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_001025572.1	Gene:	acat1 / 594960	XenbaseID:	XB-GENE-977282	Length:	420	Species:	Xenopus tropicalis

Alignment Length:	412	Identity:	273/412 - (66%)
Similarity:	333/412 - (80%)	Gaps:	3/412 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SARLLQATRRWS-AHRNYSSK--IAEVVVVSAARTPIGSFQSQLAPLTATQLGARAIEAAIEKAG 63
            :|||..:||... .||.:.|:  :.|||:.|||||||||||..|:.|.||:||:.||:||:|:||
Frog     9 AARLSHSTRALHYTHRGHVSQRTLNEVVIASAARTPIGSFQGSLSSLPATKLGSIAIKAAVERAG 73

  Fly    64 IAKTDVQEVIMGNVVSAGLGQAPARQAAIFAGLPTNVCCTTVNKVCSSGMKAVMLGAQSLMLGYA 128
            |...:|:||.||||:.||.||||:|||.:.|||..:...||:||||:||||::||.|||||.|:.
Frog    74 IPGDEVKEVYMGNVLQAGQGQAPSRQATLGAGLAISTPTTTINKVCASGMKSIMLAAQSLMCGHQ 138

  Fly   129 DVVVAGGMESMSNVPYYLKRGATPYGGVNLTDGIVFDGLWDVYNKFHMGNCAENTAKKLEITRQQ 193
            .|:|||||||||||||.:.|||||||||.|.|.||.|||.|||||||||||||||||||.|:|::
Frog   139 QVMVAGGMESMSNVPYCMSRGATPYGGVKLEDIIVKDGLTDVYNKFHMGNCAENTAKKLSISREE 203

  Fly   194 QDDFAIESYKRSAAAWANKVFQDEIAPVKIQQKRKPEIVISEDEEYKRVNFDKFGQLATVFQREN 258
            ||.|||.||.||.|||.:.:..:||..|.|.||.:|:|::.||||||||:|.||.:|.||||::|
Frog   204 QDSFAINSYTRSKAAWDSGLIANEIVSVTISQKGRPDIIVQEDEEYKRVDFSKFSKLKTVFQKDN 268

  Fly   259 GTVTAGNASTLNDGGAAVVLMSAEAAQKAGIKPLARIVAFQDAETDPIDFPIAPALAIPKLLKRA 323
            |||||.||||||||.||:|||:|.||.:..:.||||||||.||..||||||||||.|:||||..|
Frog   269 GTVTAANASTLNDGAAALVLMTAGAASRLNVTPLARIVAFADAAVDPIDFPIAPAYAVPKLLSEA 333

  Fly   324 GVRKEDVAMWEVNEAFSLVVLANIKKLDVDPAKVNVHGGAVSIGHPIGMSGARLVAHLSHSLKKG 388
            |::|||:||||:|||||:|||||:|.||:|||:|||:|||||:||||||||||:|.|::|.||||
Frog   334 GLKKEDIAMWEINEAFSVVVLANVKMLDIDPARVNVNGGAVSLGHPIGMSGARIVGHMAHVLKKG 398

  Fly   389 ELGCASICNGGGGASSILIEKL 410
            :.|.|.|||||||||::|||||
Frog   399 QFGIAGICNGGGGASAVLIEKL 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10932	NP_001284987.1	PLN02644	24..410	CDD:215347	263/385 (68%)
CG10932	NP_001284987.1	thiolase	26..409	CDD:238383	260/382 (68%)
acat1	NP_001025572.1	thiolase	36..419	CDD:238383	260/382 (68%)
acat1	NP_001025572.1	Coenzyme A binding. /evidence=ECO:0000250\|UniProtKB:P24752	251..253		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	341	1.000	Domainoid score	I1085
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6
Inparanoid	1	1.050	544	1.000	Inparanoid score	I1145
OMA	1	1.010	-	-		QHG60894
OrthoDB	1	1.010	-	-		D1011220at2759
OrthoFinder	1	1.000	-	-		FOG0000432
OrthoInspector	1	1.000	-	-		oto104635
Panther	1	1.100	-	-	LDO	PTHR18919
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1511
SonicParanoid	1	1.000	-	-		X2197
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110