Protein Alignment Ir7g and grin2bb

DIOPT Version :9

• Sequence 1: NP_001368933.1
• Gene: Ir7g / 31694
• FlyBaseID: FBgn0029968
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_001121809.1
• Gene: grin2bb / 559976
• ZFINID: ZDB-GENE-061207-27
• Length: 1770
• Species: Danio rerio
• Alignment Length: 645
• Identity: 115/645 - (17%)
• Similarity: 214/645 - (33%)
• Gaps: 233/645 - (36%)

  Fly    57 SPMNFYRNIMQLLYE------SVD--TMIVQLVLVELGRPR---RIAGPRTHNLLLVDSLDALLD 110
            :|....|.:|.:.:|      |.|  .|..:||::.|.:.|   |:.  :..|..|.........
Zfish   408 NPNEVLRYLMNVTFEGRNLSFSEDGFQMHPKLVIILLNKERQYERVG--KWENGSLAMKYHVWPR 470

  Fly   111 IEIHTYTAQSDTSEYYFIFLQQRDALIPHDMQGVFAYCWRHQLINCNVMTQSSGGQVLLHTYFPY 175
            .|:::...:.:......:.|::...:|..|:..:...|.|:.:
Zfish   471 FELYSDAEEREDDHLSIVTLEEAPFVIVEDVDPLSGTCMRNTV---------------------- 513

  Fly   176 APGQCNDSQPTRINMFLGESWKHRDYFPSKLHNLNGCPLIVLARKVSPFLDLDEG---QRELRGL 237
                     |.|..:              ||.||.|                |.|   :|..:|.
Zfish   514 ---------PCRKQL--------------KLQNLTG----------------DSGIYIKRCCKGF 539

  Fly   238 EGRLLQELSRRMNFSIQF----SGLQDQLKNRTTWTEKQLLQKLVQERI---AHLAIGYV---RK 292
            ...:|:::::.:.|:...    :|...: |...||      ..:|.|.:   ||:|:|.:   .:
Zfish   540 CIDILKKIAKSVKFTYDLYLVTNGKHGK-KINGTW------NGMVGEVVLKNAHMAVGSLTINEE 597

  Fly   293 RIQYATNLTPVFPHYSNRVVGCLLLNAHNLTSLEIWSFPFQALTWICLVFSFLSIS--------- 348
            |.:......|    :....:..::..::...|...:..||.|..|:.:....|.:|
Zfish   598 RSEVIDFSVP----FIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEY 658

  Fly   349 --------CLALLHXRGAGDRLALVLAVY-----AASLGLPIDPPERPSLQLLFASWLIFGLIVR 400
                    |||... .| |....:..|::     ..:..:|:..|:..:.:::.:.|..|.:|..
Zfish   659 FSPVGYNRCLADGREPG-GPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFL 722

  Fly   401 SMYSA-LLFFILRYHLHQRLPGNLQD--LTHGD-------YAAVMGRTTLQDLR----EVPSLQD 451
            :.|:| |..|:::.....::.| |.|  ..|.:       :..|...:|.:::|    |:.|...
Zfish   723 ASYTANLAAFMIQEEYVDQVTG-LSDKKFQHPNDFSPPFRFGTVPNGSTERNIRNNYKEMHSYMT 786

  Fly   452 LLGLKSVIVTSEREEEVLRTL----------DRCTLR------EGA-----GSHPLF----FGL- 490
            ....|:|       .|.|.:|          |...|.      ||.     ||..:|    :|:
Zfish   787 SFHQKNV-------NEALHSLKSGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGYIFATTGYGIA 844

  Fly   491 ISQD---------ALLHLTQRGHRAGAYHIIPQDVLEQQLAIYL------QKHSHLASHLDHLVM 540
            |.:|         |:|.|...|.            :|:..|::|      :|:..::|.||
Zfish   845 IQKDSGWKRAVDLAILQLFGDGE------------MEELEALWLTGICHNEKNEVMSSQLD---- 893

  Fly   541 SIRSVGLVHHWAGQMASERYFRSRFLYREKRIRQPDLWAVYILTAGLYLLSLVVFICELL 600
                   |.:.||                         ..|:|.|.: .|||:.||.|.|
Zfish   894 -------VDNMAG-------------------------VFYMLGAAM-ALSLITFIAEHL 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7g	NP_001368933.1	None
grin2bb	NP_001121809.1	PBP1_iGluR_NMDA_NR2	107..470	CDD:107373	14/63 (22%)
		ANF_receptor	138..442	CDD:279440	9/33 (27%)
		PBP2_iGluR_NMDA_Nr2	482..882	CDD:270436	83/492 (17%)
		Lig_chan	636..908	CDD:278489	59/328 (18%)
		NMDAR2_C	919..1770	CDD:287527	1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591415
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840