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Protein Alignment Ir7g and Grik2

DIOPT Version :9

Sequence 1:	NP_001368933.1	Gene:	Ir7g / 31694	FlyBaseID:	FBgn0029968	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	NP_062182.1	Gene:	Grik2 / 54257	RGDID:	2733	Length:	908	Species:	Rattus norvegicus

Alignment Length:	686	Identity:	133/686 - (19%)
Similarity:	231/686 - (33%)	Gaps:	219/686 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VTSLLNFESMKYI------------GAQTQAASINHHVAQALRVFIEDFYQRIAPAFIVVLSCRR 55
            |:|::...||:.:            |..|..|::.:.....:.|.::.|.|....:    |.|.|
  Rat   289 VSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSS----LQCNR 349

  Fly    56 PSPMNFYRNIMQLLYESVDTMIVQLVLVELGRPRRIAGPRTHNLLLVDSLDAL------LDIEIH 114
            ..|..|....|.|:.|:...          |...||...:|:.|.....||.:      |: :|.
  Rat   350 HKPWRFGTRFMSLIKEAHWE----------GLTGRITFNKTNGLRTDFDLDVISLKEEGLE-KIG 403

  Fly   115 TYTAQSDTSEYYFIFLQQRDALIPHDMQGVFAYCWRHQLINCNVMTQSSGGQVLLHTYFPYAPGQ 179
            |:...|..:                                   ||:|..|:          |..
  Rat   404 TWDPASGLN-----------------------------------MTESQKGK----------PAN 423

  Fly   180 CNDSQPTRINMFLGESWKHRDYFPSKLHNLNGCPLIVLARKVSPFLDLDEGQRELRG---LEG-- 239
            ..||                         |:...|||......|::...:..:.|.|   .||
  Rat   424 ITDS-------------------------LSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYC 463

  Fly   240 -RLLQELSRRMNFSIQFS-------GLQDQLKNRTTWTEKQLLQKLVQERIAHLAIGYVRKRIQY 296
             .||:|||..:.|:.:..       |.||.:..:.....::|:.......:|.|||.|||:::
  Rat   464 IDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKV-- 526

  Fly   297 ATNLTPVFPHYSNRVVG-CLLLNAHNLTSLEIWSF--PFQALTWICLVFSFLSISCLALLHXRGA 358
             .:.:..|     ..:| .:|....|.|:..::||  |.....|:.::.:.|.:||:..:..|
  Rat   527 -IDFSKPF-----MTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIAR-- 583

  Fly   359 GDRLALVLAVYAASLGLPIDP------------------------------PERPSLQLLFASWL 393
                   .:.|......|.:|                              |:..|.:::...|.
  Rat   584 -------FSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMRQGSELMPKALSTRIVGGIWW 641

  Fly   394 IFGLIVRSMYSALLFFILRYHLHQRLPGNLQDL---THGDYAAVMGRTTLQDLREVP-SLQDLLG 454
            .|.||:.|.|:|.|...|.....:....:..||   |..:|.||....|:...::.. |..|.:.
  Rat   642 FFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMW 706

  Fly   455 L------KSVIVTSERE--EEVLRTLDRCTLREGAGSHPLFFGLISQDALLHLTQ-------RGH 504
            .      :||:|.|..|  :.|| |.|...|.|   |..:.|  ::| ...:|||       :|:
  Rat   707 AFMSSRRQSVLVKSNEEGIQRVL-TSDYAFLME---STTIEF--VTQ-RNCNLTQIGGLIDSKGY 764

  Fly   505 RAGAYHIIPQDVLEQQLAIYLQKHSHLASHLDHLVMSIRSVGLVHHWAGQMASERYFRSRFLYRE 569
            ..|.....|          |..|       :...::.::..|.:|     |..|:::|......|
  Rat   765 GVGTPMGSP----------YRDK-------ITIAILQLQEEGKLH-----MMKEKWWRGNGCPEE 807

  Fly   570 K-----RIRQPDLWAVYILTAGLYLLSLVVFICELL 600
            :     .:...::..::|:.|...:||:.|.:.|.|
  Rat   808 ESKEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFL 843

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.