Protein Alignment Ir7g and Ekar

DIOPT Version :10

• Sequence 1: NP_001368933.1
• Gene: Ir7g / 31694
• FlyBaseID: FBgn0029968
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Alignment Length: 615
• Identity: 118/615 - (19%)
• Similarity: 217/615 - (35%)
• Gaps: 172/615 - (27%)

  Fly   101 LVDSLDA-----LLDIEIHTYTAQSDTSEYYF------------IFLQQRDALIPHDMQGVFAYC 148
            |||:.|.     |.||.::        |.:.|            ..|:...||: .|...|||..
  Fly   253 LVDTADVGVKQILKDIGLY--------SHHIFKKPYLNLHIKKSTILESEPALM-FDSVYVFAIG 308

  Fly   149 WR-----HQL----INCNVMTQSSGGQVLLHTYFPY----------APGQCNDSQPTRINMFL-- 192
            .:     |.|    |:|.......||..|::    |          .|.|..|.|..:..:.|
  Fly   309 LQTLEQSHSLTLLNISCEEENSWDGGLSLIN----YLNAVEWKGLTGPIQFKDGQRVQFKLDLIK 369

  Fly   193 ---------GESWKHRD--------YFPSKLHNLNGCPLIVLARKVSPFLDLD-----EGQRELR 235
                     ||...|..        :|.:...|:.   |:|:....:|::.:.     .|.....
  Fly   370 LKQHSIVKVGEWTPHGHLNITEPSMFFDAGSMNVT---LVVITILETPYVMMHYGKNFTGNERFY 431

  Fly   236 GLEGRLLQELSRRMNFSIQFSGLQDQ---LKNRTTWTEKQLLQKLVQERIAHLAIGYVRKRIQYA 297
            |....:|:.:||.:.|......:.|:   .|:..|.....::.:|::.: |.||:|.:  .|.||
  Fly   432 GFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYK-ADLAVGSM--TITYA 493

  Fly   298 TNLTPVFPH-YSNRVVGCL----------LLNAHNLTSLEIWSFPFQA--LTWICLV----FSFL 345
            ......|.. :.|..:..|          |.:..|..::|||.:...|  |..:|:.    .|.:
  Fly   494 RESVIDFTKPFMNLGISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPI 558

  Fly   346 SISCLAL--LHXRGAGDRLALVLAVYAASLGL-----PIDPPERPSLQLLFASWLIFGLIVRSMY 403
            ...|:..  |.....|::.:|..:.: .::|.     |...|...|.:::.::|..|.||:.:.|
  Fly   559 EWKCINACDLENISIGNQFSLTDSFW-FTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASY 622

  Fly   404 SALLFFILRYHLHQRLPGNLQDL---THGDYAAVMGRTTLQDLREVPSLQDLLGLKSVIVTSERE 465
            :|.|...|..........|.:||   |...|..:...:|:...|:           |||   |..
  Fly   623 TANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFFRD-----------SVI---ETY 673

  Fly   466 EEVLRTLDRCTLREGAGSHPLFFGLISQDALLHLTQRGHRAGAY----------HIIPQDVLEQQ 520
            :::.|::|        ...|..|....:|.:..:.|     |.|          :|:.:|....|
  Fly   674 KKIWRSMD--------NKKPSAFTTTYEDGIKRVNQ-----GNYAFLMESTMLDYIVQRDCNLTQ 725

  Fly   521 L---------AIYLQKHSHLASHLDHLVMSIRSVGLVHHWAGQMASERYFRS--RFLYREKRIRQ 574
            :         .|...|.|.....:...::.::..|.:     ||..::::::  ....|:...:|
  Fly   726 IGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDI-----QMLYDKWWKNTDETCTRKNTSKQ 785

  Fly   575 --------PDLWAVY-ILTAGLYLLSLVVF 595
                    ..:..|: :|.||:.:.::|.|
  Fly   786 SKANSLGLESIGGVFVVLIAGIIVAAVVAF 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7g	NP_001368933.1	None
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	32/149 (21%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	77/407 (19%)
		Lig_chan	532..806	CDD:459656	55/306 (18%)