DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ir7g and Gria3

DIOPT Version :9

Sequence 1:NP_001368933.1 Gene:Ir7g / 31694 FlyBaseID:FBgn0029968 Length:607 Species:Drosophila melanogaster
Sequence 2:NP_001106213.1 Gene:Gria3 / 29628 RGDID:70958 Length:888 Species:Rattus norvegicus


Alignment Length:506 Identity:94/506 - (18%)
Similarity:176/506 - (34%) Gaps:156/506 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 QTQAASI-NHHVAQALRVFIEDFYQRIAPAFIVVLSCRRPSPMNFYRNIMQLLYESVDTMIVQLV 81
            |..|.|: |....|..|..||:..:|....:::  .|.               .|.::|::.|:|
  Rat   181 QVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLI--DCE---------------VERINTILEQVV 228

  Fly    82 LVELGRPRRIAGPRTHNLLL-VDSLDALLDIEIH---------TYTAQSDTSEYY---FIFLQQR 133
            :  ||:..|    ..|.:|. :...|.||:..:|         ....::...:.:   ::.|.:|
  Rat   229 I--LGKHSR----GYHYMLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDER 287

  Fly   134 D------------ALIPHDMQGVFAYCWRH-QLINCNVMTQSSGGQVLLHTYFPYAPG------- 178
            :            :.:.||...|.|..:|: :....:|..:.|.|..|.:...|::.|       
  Rat   288 EFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERAL 352

  Fly   179 ---QCN--------DSQPTRIN-------MFLGES-----WKHRDYF----PSKLHNLNGC---- 212
               |..        |:...|.|       |.:..|     |...:.|    ..::.|.:..    
  Rat   353 KMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENR 417

  Fly   213 PLIVLARKVSPFLDLDEGQRELRG---LEG---RLLQELSRRMNFSIQFSGLQD---QLKNRTTW 268
            .::|.....||::...:...:|.|   .||   .|..|:::.:....:.|.:.|   ..::..|.
  Rat   418 TIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETK 482

  Fly   269 TEKQLLQKLVQER----IAHLAIGYVRKR-IQYATNLTPVFPHYSNRVVGCLLLNAHNLTSLEIW 328
            ....::.:||..|    :|.|.|..||:. |.::.      |..|..:  .:::.....:...::
  Rat   483 IWNGMVGELVYGRADIAVAPLTITLVREEVIDFSK------PFMSLGI--SIMIKKPQKSKPGVF 539

  Fly   329 SF--PFQALTWICLVFSFLSISCLALLHXRGAGDRLALVLAVYAASL-------GLPIDPPERPS 384
            ||  |.....|:|:||:::.:|.:..|..|         .:.|...|       ..|..||:.|:
  Rat   540 SFLDPLAYEIWMCIVFAYIGVSVVLFLVSR---------FSPYEWHLEDNNEEPRDPQSPPDPPN 595

  Fly   385 LQLLFAS----------------------------WLIFGLIVRSMYSALL 407
            ...:|.|                            |..|.||:.|.|:|.|
  Rat   596 EFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANL 646

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir7gNP_001368933.1 None
Gria3NP_001106213.1 PBP1_iGluR_AMPA_GluR3 29..400 CDD:107382 43/241 (18%)
ANF_receptor 40..383 CDD:279440 40/224 (18%)
PBP2_iGluR_AMPA 416..799 CDD:270433 49/248 (20%)
Glutamate binding 502..504 0/1 (0%)
Lig_chan 548..829 CDD:278489 23/108 (21%)
Glutamate binding 680..681
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166350164
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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