Protein Alignment Ir7g and Grik1

DIOPT Version :10

• Sequence 1: NP_001368933.1
• Gene: Ir7g / 31694
• FlyBaseID: FBgn0029968
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_001104587.1
• Gene: Grik1 / 29559
• RGDID: 2732
• Length: 949
• Species: Rattus norvegicus
• Alignment Length: 710
• Identity: 136/710 - (19%)
• Similarity: 236/710 - (33%)
• Gaps: 224/710 - (31%)

  Fly     7 LNFESMKYIGAQTQAASI----NHHVAQALRVFIEDFYQRIAPAFIVVLSCRRPSPMNFYRNIMQ 67
            |:.|..:|.|.......:    |.||:..:..:..:..|  ||          |.|.....:.|.
  Rat   265 LDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQ--AP----------PRPETGLLDGMM 317

  Fly    68 -----LLYESVDTMIV------QLVLVEL----GRPRRIAGPRTHNLL---------------LV 102
                 |:|::|..:.:      ||.:..|    .:|.|: |||..||:               ..
  Rat   318 TTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPWRL-GPRFMNLIKEARWDGLTGRITFNKT 381

  Fly   103 DSLDALLDIEIHTYTAQSDTSEYYFIFLQQRDALIPHDMQGVFAYCWRHQLINCNVMTQSSGGQV 167
            |.|....|::|              |.|::..                         |:.:.|:|
  Rat   382 DGLRKDFDLDI--------------ISLKEEG-------------------------TEKASGEV 407

  Fly   168 LLHTYFPYAP-GQCNDSQPTRINMFLGESWKHRDYFPSKLHNLNGCPLIVLARKVSPFLDLDEGQ 231
            ..|.|..:.. |..|.:  :.:||..|    :||...:...:|....|||......|::...:..
  Rat   408 SKHLYKVWKKIGIWNSN--SGLNMTDG----NRDRSNNITDSLANRTLIVTTILEEPYVMYRKSD 466

  Fly   232 RELRG---LEG---RLLQELSRRMNFSIQFS-------GLQDQLKNRTTWTEKQLLQKLVQERIA 283
            :.|.|   .||   .||:|||..:.|.....       |.|:. |.......|:|:.......:|
  Rat   467 KPLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQND-KGEWNGMVKELIDHRADLAVA 530

  Fly   284 HLAIGYVRKRIQYATNLTPVFPHYSNRVVG-CLLLNAHNLTSLEIWSF--PFQALTWICLVFSFL 345
            .|.|.|||:::   .:.:..|     ..:| .:|....|.|:..::||  |.....|:.::.:.|
  Rat   531 PLTITYVREKV---IDFSKPF-----MTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACL 587

  Fly   346 SISCLALLHXRGAGDRLALVLAVYAASLGLPIDP------------------------------P 380
            .:||:..:. |         ...|......|.:|                              |
  Rat   588 GVSCVLFVIAR---------FTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMP 643

  Fly   381 ERPSLQLLFASWLIFGLIVRSMYSALLFFILRYHLHQRLPGNLQDL---THGDYAAVMGRTTLQD 442
            :..|.:::...|..|.||:.|.|:|.|...|.....:....:..||   |..:|.||...:|:..
  Rat   644 KALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTF 708

  Fly   443 LREVPSLQDLLGLKSVIVT---------SEREEEVLRTLDRCTLREGAGSHPLFFGLISQDALLH 498
            .:           ||.|.|         |.::..:::..|....|.....:.|   |:...::.:
  Rat   709 FK-----------KSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYAL---LMESTSIEY 759

  Fly   499 LTQR--------------GHRAGAYHIIPQDVLEQQLAIYLQKHSHLASHLDHLVMSIRSVGLVH 549
            :|||              |:..|.....|          |..|       :...::.::..|.:|
  Rat   760 VTQRNCNLTQIGGLIDSKGYGVGTPIGSP----------YRDK-------ITIAILQLQEEGKLH 807

  Fly   550 HWAGQMASERYFRSRFLYRE-----KRIRQPDLWAVYILTAGLYLLSLVVFICELLASRR 604
                 |..|:::|......|     ..:...::..::|:.|...:||:.|.|.|.|...|
  Rat   808 -----MMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFLYKSR 862

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7g	NP_001368933.1	None
Grik1	NP_001104587.1	PBP1_iGluR_Kainate	38..431	CDD:380605	41/219 (19%)
		Periplasmic_Binding_Protein_Type_2	446..815	CDD:473866	80/422 (19%)