Protein Alignment Ir7g and GRIK5

DIOPT Version :9

• Sequence 1: NP_001368933.1
• Gene: Ir7g / 31694
• FlyBaseID: FBgn0029968
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: XP_011525167.1
• Gene: GRIK5 / 2901
• HGNCID: 4583
• Length: 982
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 111/572 - (19%)
• Similarity: 195/572 - (34%)
• Gaps: 189/572 - (33%)

  Fly   146 AYCWRH--QLINCNVMTQSSG--GQVLLHTYFPYAPGQCNDSQPTRINMFLGESWK--HRD---Y 201
            |..|.|  .|:|...|.:..|  |:|..:          :..|.|...:.:.|..:  ||:   :
Human   337 ANIWPHGTSLMNYLRMVEYDGLTGRVEFN----------SKGQRTNYTLRILEKSRQGHREIGVW 391

  Fly   202 FPSKLHNLNGCPLIV-----LARKV--------------SPFLDLDEGQRELRGLEGRLLQELSR 247
            :.::...:|...|.:     ||.|.              .|......|.....|....:|:||:.
Human   392 YSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAE 456

  Fly   248 RMNFSIQFSGLQDQL----KNRTTWTEKQLLQKLVQERIAHLAIGYV------RKRIQYATNLTP 302
            .:.|..:...::|.|    :...:||  .::.:|:..:.|.||:...      .|.|.::.
Human   457 LLRFRYRLRLVEDGLYGAPEPNGSWT--GMVGELINRQKADLAVAAFTITAEREKVIDFSK---- 515

  Fly   303 VFPHYSNRVVGCLLLNAHNLTSLEIWSF--PFQALTWICLVFSFLSISCLALLHXRGAGDRLALV 365
              |..:..:  .:|...|.......:||  ||....|:.::.::|::||:..|. |
Human   516 --PFMTLGI--SILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAAR--------- 567

  Fly   366 LAVY----------------------AASLGLPID---------PPERPSLQLLFASWLIFGLIV 399
            |:.|                      ..||..|:.         .|...|.:.:...|..|.||:
Human   568 LSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLII 632

  Fly   400 RSMYSALLFFIL---RYHLHQRLPGNLQDLTHGDYAAVMGRTTL---QDLR---------EVPSL 449
            .|.|:|.|...|   |..:......:|.|.|:.:|..:...:|:   |:.|         .:.|.
Human   633 ISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSK 697

  Fly   450 QDLLGLKSVIVTSEREEEVLRTLD------------------RCTLREGAGSHPLFFGLISQDAL 496
            |..:.:||.      ||.:.|.|:                  .|.|.:..|.
Human   698 QPSVFVKST------EEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQIGGL------------- 743

  Fly   497 LHLTQRGHRAGAYHIIP-----QDVLEQQLAI-YLQKHSHLASHLDHLVMSIRSVGLVHHW--AG 553
              |..:|:..|    :|     :|  |..||| .||:::.|..             |...|  .|
Human   744 --LDTKGYGIG----MPLGSPFRD--EITLAILQLQENNRLEI-------------LKRKWWEGG 787

  Fly   554 QMASERYFRSRFLYREKRIRQPDLWAVYI-LTAGLYLLSLVVFICELLASRR 604
            :...|...|::.|..|      ::..::| |..|| ::::.|.:.|.:.|.|
Human   788 RCPKEEDHRAKGLGME------NIGGIFIVLICGL-IIAVFVAVMEFIWSTR 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7g	NP_001368933.1	None
GRIK5	XP_011525167.1	PBP1_iGluR_Kainate_KA1_2	25..399	CDD:107389	14/71 (20%)
		ANF_receptor	42..379	CDD:279440	11/51 (22%)
		Periplasmic_Binding_Protein_Type_2	414..785	CDD:304360	80/429 (19%)
		Lig_chan	546..816	CDD:278489	62/324 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156219
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840