Protein Alignment Ir7g and GRIA1

DIOPT Version :9

• Sequence 1: NP_001368933.1
• Gene: Ir7g / 31694
• FlyBaseID: FBgn0029968
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_001244950.1
• Gene: GRIA1 / 2890
• HGNCID: 4571
• Length: 916
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 81/455 - (17%)
• Similarity: 158/455 - (34%)
• Gaps: 117/455 - (25%)

  Fly   213 PLIVLARKVSPFLDLDEGQRELRGLEGRLLQELSRRMNFSIQFSGLQD---QLKNRTTWTEKQLL 274
            |.::|.:..:.|    ||.....|....|..|:::.:.:|.:...:.|   ..::..|.....::
Human   428 PYVMLKKNANQF----EGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMV 488

  Fly   275 QKLVQER----IAHLAIGYVRKR-IQYATNLTPVFPHYSNRVVGCLLLNAHNLTSLEIWSF--PF 332
            .:||..|    :|.|.|..||:. |.::.      |..|..:  .:::.....:...::||  |.
Human   489 GELVYGRADVAVAPLTITLVREEVIDFSK------PFMSLGI--SIMIKKPQKSKPGVFSFLDPL 545

  Fly   333 QALTWICLVFSFLSISCLALLHXR--------------------------GAGDRLALVLAVYAA 371
            ....|:|:||:::.:|.:..|..|                          |..:.|...|..:..
Human   546 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ 610

  Fly   372 SLGLPIDPPERPSLQLLFASWLIFGLIVRSMYSALLFFILRYHLHQRLPGNLQDL---THGDYAA 433
            . |..|. |...|.:::...|..|.||:.|.|:|.|...|..........:.:||   |...|..
Human   611 Q-GCDIS-PRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGT 673

  Fly   434 VMGRTTLQDLREVPSLQDLLGLKSVIVTSEREEEVLRTLDRCTLREGAGSHPLFFGLISQDALLH 498
            :...:|.:..|           :|.|...|:....:::           :.|..|...:::.::.
Human   674 LEAGSTKEFFR-----------RSKIAVFEKMWTYMKS-----------AEPSVFVRTTEEGMIR 716

  Fly   499 LTQ-RGHRAGAYHIIPQDVLEQQ----------------LAIYLQKHSHLASHLDHLVMSIRSVG 546
            :.: :|..|........:.:||:                ..|...|.|.|.:.::..|:.:...|
Human   717 VRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQG 781

  Fly   547 LVHHWAGQMASERYFRSRFLY--------------REKRIRQPDLWAV-YILTAGLYLLSLVVFI 596
            |:..          .::::.|              :...:...::..| |||..||.|..||..|
Human   782 LLDK----------LKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALI 836

  Fly   597  596
            Human   837  836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7g	NP_001368933.1	None
GRIA1	NP_001244950.1	PBP1_iGluR_AMPA_GluR1	36..399	CDD:107385
		ANF_receptor	47..382	CDD:279440
		PBP2_iGluR_AMPA_GluR1	416..797	CDD:270447	71/414 (17%)
		Lig_chan	548..827	CDD:278489	50/312 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156057
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840