Protein Alignment Ir7g and Grik5

DIOPT Version :10

• Sequence 1: NP_001368933.1
• Gene: Ir7g / 31694
• FlyBaseID: FBgn0029968
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: XP_030098003.1
• Gene: Grik5 / 14809
• MGIID: 95818
• Length: 1003
• Species: Mus musculus
• Alignment Length: 572
• Identity: 110/572 - (19%)
• Similarity: 195/572 - (34%)
• Gaps: 189/572 - (33%)

  Fly   146 AYCWRH--QLINCNVMTQSSG--GQVLLHTYFPYAPGQCNDSQPTRINMFLGESWK--HRD---Y 201
            |..|.|  .|:|...|.:..|  |:|..:          :..|.|...:.:.|..:  ||:   :
Mouse   360 ANIWPHGTSLMNYLRMVEYDGLTGRVEFN----------SKGQRTNYTLRILEKSRQGHREIGVW 414

  Fly   202 FPSKLHNLNGCPLIV-----LARKV--------------SPFLDLDEGQRELRGLEGRLLQELSR 247
            :.::...:|...|.:     ||.|.              .|......|.....|....:|:||:.
Mouse   415 YSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAE 479

  Fly   248 RMNFSIQFSGLQDQL----KNRTTWTEKQLLQKLVQERIAHLAIGYV------RKRIQYATNLTP 302
            .:.|..:...::|.|    :...:||  .::.:|:..:.|.||:...      .|.|.::.
Mouse   480 LLRFRYRLRLVEDGLYGAPEPNGSWT--GMVGELINRQKADLAVAAFTITAEREKVIDFSK---- 538

  Fly   303 VFPHYSNRVVGCLLLNAHNLTSLEIWSF--PFQALTWICLVFSFLSISCLALLHXRGAGDRLALV 365
              |..:..:  .:|...|.......:||  ||....|:.::.::|::||:..|..|
Mouse   539 --PFMTLGI--SILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAAR--------- 590

  Fly   366 LAVY----------------------AASLGLPID---------PPERPSLQLLFASWLIFGLIV 399
            |:.|                      ..||..|:.         .|...|.:.:...|..|.||:
Mouse   591 LSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLII 655

  Fly   400 RSMYSALLFFIL---RYHLHQRLPGNLQDLTHGDYAAVMGRTTL---QDLR---------EVPSL 449
            .|.|:|.|...|   |..:......:|.|.|:.:|..:...:|:   |:.|         .:.|.
Mouse   656 ISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSK 720

  Fly   450 QDLLGLKSVIVTSEREEEVLRTLD------------------RCTLREGAGSHPLFFGLISQDAL 496
            |..:.:||.      ||.:.|.|:                  .|.|.:..|.
Mouse   721 QPSVFVKST------EEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQIGGL------------- 766

  Fly   497 LHLTQRGHRAGAYHIIP-----QDVLEQQLAI-YLQKHSHLASHLDHLVMSIRSVGLVHHW--AG 553
              |..:|:..|    :|     :|  |..||| .||:::.|..             |...|  .|
Mouse   767 --LDTKGYGIG----MPLGSPFRD--EITLAILQLQENNRLEI-------------LKRKWWEGG 810

  Fly   554 QMASERYFRSRFLYREKRIRQPDLWAVY-ILTAGLYLLSLVVFICELLASRR 604
            :...|...|::.|..|      ::..:: :|..|| ::::.|.:.|.:.|.|
Mouse   811 RCPKEEDHRAKGLGME------NIGGIFVVLICGL-IIAVFVAVMEFIWSTR 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7g	NP_001368933.1	None
Grik5	XP_030098003.1	PBP1_iGluR_Kainate_KA1_2	23..424	CDD:380616	14/73 (19%)
		Periplasmic_Binding_Protein_Type_2	437..808	CDD:473866	80/429 (19%)