Protein Alignment Ir7g and Grik2

DIOPT Version :9

• Sequence 1: NP_001368933.1
• Gene: Ir7g / 31694
• FlyBaseID: FBgn0029968
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: XP_011241422.1
• Gene: Grik2 / 14806
• MGIID: 95815
• Length: 943
• Species: Mus musculus
• Alignment Length: 712
• Identity: 135/712 - (18%)
• Similarity: 236/712 - (33%)
• Gaps: 236/712 - (33%)

  Fly     3 VTSLLNFESMKYI------------GAQTQAASINHHVAQALRVFIEDFYQRIAPAFIVVLSCRR 55
            |:|::...||:.:            |..|..|::.:.....:.|.::.|.|....:    |.|.|
Mouse   289 VSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSS----LQCNR 349

  Fly    56 PSPMNFYRNIMQLLYESVDTMIVQLVLVELGRPRRIAGPRTHNLLLVDSLDAL------LDIEIH 114
            ..|..|....|.|:.|:...          |...||...:|:.|.....||.:      |: :|.
Mouse   350 HKPWRFGTRFMSLIKEAHWE----------GLTGRITFNKTNGLRTDFDLDVISLKEEGLE-KIG 403

  Fly   115 TYTAQSDTSEYYFIFLQQRDALIPHDMQGVFAYCWRHQLINCNVMTQSSGGQVLLHTYFPYAPGQ 179
            |:...|..:                                   ||:|..|:          |..
Mouse   404 TWDPSSGLN-----------------------------------MTESQKGK----------PAN 423

  Fly   180 CNDSQPTRINMFLGESWKHRDYFPSKLHNLNGCPLIVLARKVSPFLDLDEGQRELRG---LEG-- 239
            ..||                         |:...|||......|::...:..:.|.|   .||
Mouse   424 ITDS-------------------------LSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYC 463

  Fly   240 -RLLQELSRRMNFSIQFS-------GLQDQLKNRTTWTEKQLLQKLVQERIAHLAIGYVRKRIQY 296
             .||:|||..:.|:.:..       |.||.:..:.....::|:.......:|.|||.|||:::
Mouse   464 IDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKV-- 526

  Fly   297 ATNLTPVFPHYSNRVVG-CLLLNAHNLTSLEIWSF--PFQALTWICLVFSFLSISCLALLHXRGA 358
             .:.:..|     ..:| .:|....|.|:..::||  |.....|:.::.::|.:||:..:. |.:
Mouse   527 -IDFSKPF-----MTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARQS 585

  Fly   359 -------------------------GDRLALVL-AVYAASLGLPIDP------------------ 379
                                     ...:.|.| :.|......|.:|
Mouse   586 KFSWFKYPNCSHYHHSQRCLCTQHLESYMELCLFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFG 650

  Fly   380 ------------PERPSLQLLFASWLIFGLIVRSMYSALLFFILRYHLHQRLPGNLQDL---THG 429
                        |:..|.:::...|..|.||:.|.|:|.|...|.....:....:..||   |..
Mouse   651 VGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKI 715

  Fly   430 DYAAVMGRTTLQDLREVP-SLQDLLGL------KSVIVTSERE--EEVLRTLDRCTLREGAGSHP 485
            :|.||....|:...::.. |..|.:..      :||:|.|..|  :.|| |.|...|.|   |..
Mouse   716 EYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVL-TSDYAFLME---STT 776

  Fly   486 LFFGLISQDALLHLTQ-------RGHRAGAYHIIPQDVLEQQLAIYLQKHSHLASHLDHLVMSIR 543
            :.|  ::| ...:|||       :|:..|.....|          |..|       :...::.::
Mouse   777 IEF--VTQ-RNCNLTQIGGLIDSKGYGVGTPMGSP----------YRDK-------ITIAILQLQ 821

  Fly   544 SVGLVHHWAGQMASERYFRSRFLYREK-----RIRQPDLWAVYILTAGLYLLSLVVFICELL 600
            ..|.:|     |..|:::|......|:     .:...::..::|:.|...:||:.|.:.|.|
Mouse   822 EEGKLH-----MMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFL 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7g	NP_001368933.1	None
Grik2	XP_011241422.1	PBP1_iGluR_Kainate	37..414	CDD:380605	29/174 (17%)
		Periplasmic_Binding_Protein_Type_2	430..835	CDD:389745	89/441 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846628
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930