Protein Alignment Ir7g and Gria2

DIOPT Version :10

• Sequence 1: NP_001368933.1
• Gene: Ir7g / 31694
• FlyBaseID: FBgn0029968
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_001344853.2
• Gene: Gria2 / 14800
• MGIID: 95809
• Length: 901
• Species: Mus musculus
• Alignment Length: 547
• Identity: 98/547 - (17%)
• Similarity: 172/547 - (31%)
• Gaps: 180/547 - (32%)

  Fly    49 VVLSCRRPSPMNFYRNIMQLLYESVDTMIV--------QLVLVELG------RPRRIAGPRTHNL 99
            |:|.|.|..           :.:.||.:|.        ..::..||      ...:..|......
Mouse   207 VILDCERDK-----------VNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGF 260

  Fly   100 LLVDSLDALLDIEIHTYT---------AQSDTSEYYFIFLQQRDALIPHDMQGVFAYCWRH---Q 152
            .:||..|:|:...|..::         |.:.|.:|        .:.:.:|...|....:|:   |
Mouse   261 QIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKY--------TSALTYDAVQVMTEAFRNLRKQ 317

  Fly   153 LINCNVMTQSSGGQVLLHTYFPYAPG----------QCN--------DSQPTRINMFLG------ 193
            .|  .:..:.:.|..|.:...|:..|          |..        |....|||..:.
Mouse   318 RI--EISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKT 380

  Fly   194 ------ESWKHRD-------YFPS--KLHNLNGCPLIVLARKVSPFL------DLDEGQRELRGL 237
                  ..|...|       ..||  ....|....::|.....||::      ::.||.....|.
Mouse   381 NGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGY 445

  Fly   238 EGRLLQELSRRMNFSIQFSGLQD---QLKNRTTWTEKQLLQKLVQER----IAHLAIGYVRKR-I 294
            ...|..|:::...|..:.:.:.|   ..::..|.....::.:||..:    ||.|.|..||:. |
Mouse   446 CVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVI 510

  Fly   295 QYATNLTPVFPHYSNRVVGCLLLNAHNLTSLEIWSF--PFQALTWICLVFSFLSISCLALLHXR- 356
            .::.      |..|..:  .:::.....:...::||  |.....|:|:||:::.:|.:..|. |
Mouse   511 DFSK------PFMSLGI--SIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRF 567

  Fly   357 -------------------------GAGDRLALVLAVYAASLGLPIDPPERPSLQLLFASWLIFG 396
                                     |..:.|...|..:... |..|. |...|.:::...|..|.
Mouse   568 SPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQ-GCDIS-PRSLSGRIVGGVWWFFT 630

  Fly   397 LIVRSMYSALLFFILRYHLHQRLPGNLQDLTHGDYAAVMGRTTLQDLREVPSLQDLLGLKSVIVT 461
            ||:.|.|:|.|...|                          |..:.:..:.|.:||
Mouse   631 LIIISSYTANLAAFL--------------------------TVERMVSPIESAEDL--------- 660

  Fly   462 SEREEEVLRTLDRCTLREGAGSHPLFF 488
            |::.|....|||       :||...||
Mouse   661 SKQTEIAYGTLD-------SGSTKEFF 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7g	NP_001368933.1	None
Gria2	NP_001344853.2	PBP1_iGluR_AMPA_GluR2	28..398	CDD:380612	34/211 (16%)
		PBP2_iGluR_AMPA	413..794	CDD:270433	61/320 (19%)