DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7g and grid2

DIOPT Version :9

Sequence 1:	NP_001368933.1	Gene:	Ir7g / 31694	FlyBaseID:	FBgn0029968	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	XP_031759030.1	Gene:	grid2 / 100487676	XenbaseID:	XB-GENE-955038	Length:	1007	Species:	Xenopus tropicalis

Alignment Length:	420	Identity:	83/420 - (19%)
Similarity:	136/420 - (32%)	Gaps:	126/420 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   207 HNLNGCPLIVLARKVSPFLDLDEG----QRELRGLEGRLLQELSRRMNFSIQFSGLQDQLKNRT- 266
            :|:.|..|.|......||:.:.|.    .::.:|....:|..||..:.|..:.....|......
Frog   436 NNMRGVVLRVATVLEEPFVMVSENVLGKPKKYQGFSIDVLDALSSYLGFKYEIYVASDHKYGSPQ 500

  Fly   267 ---TWTE--KQLLQKLVQERIAHLAIGYVRKRIQYATNLTPVFPHYSNRVVGCLLLNAHNLTSLE 326
               :|..  .:||.|.....|:.|.|...|:.:   .:.|..:..||   ||.||..|.....:.
Frog   501 ADGSWNGLIGELLLKRADMGISALTITPDRENV---VDFTTRYMDYS---VGVLLRKAEKTVDMF 559

  Fly   327 IWSFPFQALTWICLVFSFLSISCLALLHXRGAGDRLALVLAVYAASLGLPIDPP----------- 380
            ....||....|.|:                 ||..|.:.|.||..:.   ::||
Frog   560 ACLAPFDLSLWACI-----------------AGTVLLVGLLVYLLNW---LNPPRLQMGSMTSTT 604

  Fly   381 -----------------ERP----SLQLLFASWLIFGLIVRSMYSALLFFILRYHLHQRLPGNLQ 424
                             |.|    :.:::..:|.:|.|||.|.|:|.|...|.....:....:||
Frog   605 LYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTISRIESSIQSLQ 669

  Fly   425 DL---THGDYAAVMGRTTLQDLREVPSLQDLLGLKSVIVTSERE---EEVLRTLDRCTLREGAGS 483
            ||   |...|..|......:.:|       :.|:...    ||:   .::.|.::|....|....
Frog   670 DLSRQTDIPYGTVFDSAVYEHVR-------VKGMNPF----ERDSMYSQMWRMINRSNGSENNVQ 723

  Fly   484 HPL---------------------FFGLISQDALLH-----LTQRGHRAGAYHIIP-QDVLEQQL 521
            ..|                     :..:..||...:     :..||:.....|..| :|:..|::
Frog   724 ESLEGIQKVKHGNYAFVWDAAVLEYIAINDQDCSFYTVGNTIADRGYGIALQHGSPYRDIFSQRI 788

  Fly   522 AIYLQKHSHLASHLDHLVMSIRSVGLVHHW 551
             :.||::..         |.|    |.|.|
Frog   789 -LELQQNGD---------MDI----LKHKW 804

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7g	NP_001368933.1	None
grid2	XP_031759030.1	Periplasmic_Binding_Protein_type1	28..429	CDD:415822
grid2	XP_031759030.1	PBP2_iGluR_delta_2	440..806	CDD:270449	82/416 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910