DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ir7c and GLR2

DIOPT Version :9

Sequence 1:NP_001245572.1 Gene:Ir7c / 31692 FlyBaseID:FBgn0029966 Length:625 Species:Drosophila melanogaster
Sequence 2:NP_001318239.1 Gene:GLR2 / 816231 AraportID:AT2G17260 Length:925 Species:Arabidopsis thaliana


Alignment Length:466 Identity:88/466 - (18%)
Similarity:160/466 - (34%) Gaps:156/466 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   236 PGGRSIHGIEGLIFRSLAERM-----------NFTIKLVEQKDKNRGEILPDGNFTGILKMMV-- 287
            |||.|:.. .|.|||:...|:           :|..::....:|.:|..:  ..|...:|::.  
plant   451 PGGTSVTP-RGWIFRNNGRRLRIGVPDRASFKDFVSRVNGSSNKVQGYCI--DVFEAAVKLLSYP 512

  Fly   288 ---------DGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVL------------------VVPS 325
                     ||..|..:         ::|:...|:...|..|:                  .:.|
plant   513 VPHEFIFFGDGLTNPNY---------NELVNKVTTGVDFDAVVGDIAIVTKRTRIVDFTQPYIES 568

  Fly   326 G-GSISPMGRLT-------RPFRYIIWSCILVSLIFGFVLICLLKITALPGLRNLVLGRRNRLPF 382
            | ..::|:.||.       |||...:|:   |:..| ||::         |....:|..|....|
plant   569 GLVVVAPVTRLNENPWAFLRPFTLPMWA---VTASF-FVIV---------GAAIWILEHRINDEF 620

  Fly   383 MG---------MW--------------ASLLGGLALYNPQRNFARYILVMWLLQTLILRAAYTGQ 424
            .|         :|              .|.||            |.:|::||...||:.::||..
plant   621 RGPPRRQIITILWFTFSTMFFSHRETTVSTLG------------RMVLLIWLFVVLIITSSYTAS 673

  Fly   425 LYLLLQDVEMRSPIKSLSEVLAKD--YEFRILPALRTIFKDSMPTTNFHAV--LSLEESLYRLRD 485
            |..:|...::.||||.:..:::..  ..|::.........|.:...:...|  .|.||....|::
plant   674 LTSILTVQQLNSPIKGVDTLISSTGRIGFQVGSFAENYMTDELNIASSRLVPLASPEEYANALQN 738

  Fly   486 EDDPGITVALL--QPTVNQFDFRSGPNKRHLTVLPDPLMTAPLTFYMRPHSY--------FKRRI 540
                |...|::  :|.::.|                  ::....|.:|...:        |.|  
plant   739 ----GTVAAIVDERPYIDLF------------------LSDYCKFAIRGQEFTRCGWGFAFPR-- 779

  Fly   541 DRLIMAMMSSGIVARYRKMYMDRI--KRVSKRRNLEP--------KPLSIWRLSGIFVCCAGLYL 595
            |..:...||:.|:.......:.:|  :.:||.....|        :.|::....|:|:......|
plant   780 DSPLAVDMSTAILGLSETGELQKIHDRWLSKSNCSSPHGSQSGDSEQLNVHSFWGMFLVVGIACL 844

  Fly   596 VALIVFILEIL 606
            |||.:...:|:
plant   845 VALFIHFFKII 855

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir7cNP_001245572.1 Lig_chan-Glu_bd 225..287 CDD:214911 14/61 (23%)
Lig_chan 343..593 CDD:278489 54/296 (18%)
GLR2NP_001318239.1 PBP1_GABAb_receptor 35..424 CDD:107361
GluR_Plant 468..808 CDD:270404 69/399 (17%)
Lig_chan 594..843 CDD:306551 54/297 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1052
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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