Protein Alignment Ir7c and gria4b

DIOPT Version :9

• Sequence 1: NP_001245572.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_997917.2
• Gene: gria4b / 336069
• ZFINID: ZDB-GENE-030131-8013
• Length: 904
• Species: Danio rerio
• Alignment Length: 639
• Identity: 119/639 - (18%)
• Similarity: 238/639 - (37%)
• Gaps: 166/639 - (25%)

  Fly    70 DRVEMTETDTDPPPPSGLTGRPIAIWFLDSLRSYFRLEMYLNQLG----------SPYKRNGFFL 124
            |:.|...:|..|...|.||...:.: ..::.|:..|.::.:::.|          :|:.:
Zfish   283 DQREYPGSDAPPKYTSALTYDGVMV-MAEAFRNLRRQKVDISRRGIAGDCLANPAAPWNQ----- 341

  Fly   125 VIYTGLEDQPMESLKIMFRRLLNMYV--LNVNVFLQRDG-----TVHLYTYYPYGPHHCQSSLPV 182
                |::         |.|.|..:::  |..||.....|     |:.::.....||....
Zfish   342 ----GID---------MERTLKQVHLQGLTGNVQFDHYGRRVNYTMDVFELKSNGPRRIG----- 388

  Fly   183 YYTAFQDLAAPANGFGLTK--PLFPRKLTNMHGCEMVVATFEHRPYVIIEDDPKTPGGRSIHGIE 245
            |:.       .|:...||:  .|.|.:.:.|....::|.|....|||:::.:.:...|...:  |
Zfish   389 YWN-------DADKLVLTQDHALLPNETSGMENRTVIVTTIMEGPYVMLKKNWEMYEGNEQY--E 444

  Fly   246 GL---IFRSLAERMNFTIKLVEQKDKNRGEILPDGNF----------TGILKMMVDGEVNLTFVC 297
            |.   :...:|:.:.|..|:         .|:|||.:          .|::..:|.|:..:....
Zfish   445 GYCVDLASEIAKHIGFKYKI---------SIVPDGKYGARDPETKIWNGMVGELVYGKAEIAVAP 500

  Fly   298 FMYSKARSDLMLPSTSYTSFPIVLVVPSGGSISP-MGRLTRPFRYIIWSCILVSLIFGFVLICLL 361
            ...:..|.:::..|..:.|..|.:::.......| :.....|..|.||.||:.:.|...|::.|:
Zfish   501 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLV 565

  Fly   362 K---------------ITALPGLRNLVLGRRNRLP-----FMGMWASLLGGLAL-----YNPQRN 401
            .               ...||.         ::.|     |..:|.||  |..:     .:|:..
Zfish   566 SRFSPYEWHTEEPEEGTDGLPS---------DQPPNEFGIFNSLWFSL--GAFMQQGCDISPRSL 619

  Fly   402 FARYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVLAKDYEFRILPALRTIFKDSMP 466
            ..|.:..:|...|||:.::||..|...|....|.|||:| :|.|||..:.    |..|:  ||..
Zfish   620 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES-AEDLAKQTDI----AYGTL--DSGS 677

  Fly   467 TTNF--HAVLSLEESLYRLRDEDDPGI---TVA---------------LLQPTVNQFDFRSGP-- 509
            |..|  .:.:::.|.::......:|.:   |.|               ||:.|:|::..:..|
Zfish   678 TKEFFRRSKIAVYEKMWSYMKSAEPTVFTKTTAEGVARVRKSKGKYAFLLESTMNEYTEQRKPCD 742

  Fly   510 ---------NKRHLTVLPDPLMTAPLTFYMRPHSYFKRRIDRLIMAMMSSGIVARYR-KMYMDRI 564
                     :|.:....|             ..|..:..::..::.:...|::.:.: |.:.|:.
Zfish   743 TMKVGGNLDSKGYGVATP-------------KGSQLRSAVNLAVLKLNEQGLLDKLKNKWWYDKG 794

  Fly   565 KRVS---KRRNLEPKPLSIWRLSGIFVCCAGLYLVALIVFILEILTTNHRRLRR 615
            :..|   ..::...:.||:..::|:|....|...:|::|.::|....:....:|
Zfish   795 ECGSGGGGEKDKSSQALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRNEAKR 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	14/74 (19%)
		Lig_chan	343..593	CDD:278489	60/309 (19%)
gria4b	NP_997917.2	Periplasmic_Binding_Protein_Type_1	28..398	CDD:324556	24/145 (17%)
		PBP2_iGluR_AMPA_GluR4	414..793	CDD:270445	79/420 (19%)
		Lig_chan	546..827	CDD:306551	61/311 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591667
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740