DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir7c and Ir7b

DIOPT Version :9

Sequence 1:	NP_001245572.1	Gene:	Ir7c / 31692	FlyBaseID:	FBgn0029966	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_572410.2	Gene:	Ir7b / 31690	FlyBaseID:	FBgn0029965	Length:	655	Species:	Drosophila melanogaster

Alignment Length:	642	Identity:	161/642 - (25%)
Similarity:	268/642 - (41%)	Gaps:	109/642 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 AVVQFPTSRESRRLHNDLIDAALGRSSGTGRIQFLLEDDRVEMTETDTDPPPPSGLTGRPIAIWF 96
            |:.|...:.|..|.....|.......|..|.::.||  |:|.|.       .|:.|..|.:.:..
  Fly    29 ALAQVVANSEMGRFKTLYIYTHTNSQSTGGHLEELL--DQVLMI-------VPNNLQARRLLLQQ 84

  Fly    97 LDSLRSYFRLEMY----LNQLGSPYKR-----NGFFLVIYTGL-EDQPMESLKIMFRRLLNMYVL 151
            ....:.|....:.    |..|.:.|.|     :....:||..: .|...|.::...|.|..:.||
  Fly    85 SMEYKPYVHAVLALVDGLPSLSAIYARIRATQDLSHTLIYMSMPTDAYGEEMQATLRFLWRLSVL 149

  Fly   152 NVNVFLQRDGT-VHLYTYYPYGP-HHCQ----SSLPVYYTAFQDLAAPANGFGLTKPLFPRKLTN 210
            ||.|.|:..|. :.:.:|:|:.. |.||    :.:..|....:..|        ::..||.||.|
  Fly   150 NVGVVLRPPGDHILMVSYFPFSALHGCQVISANVVNRYQVGTKRWA--------SQDYFPSKLGN 206

  Fly   211 MHGCEMVVATFEHRPYVIIEDDPKTPGGRSIHGIEGLIFRSLAERMNFTIKLVEQKDKNRGEILP 275
            .:||.:..||:|..||::...|    |..|..||||.:.:.:||.:|||:.|...   |:.|:|.
  Fly   207 FYGCLLTCATWEDMPYLVWRPD----GSGSFVGIEGALLQFMAENLNFTVGLYWM---NKEEVLA 264

  Fly   276 DGNFTG-ILKMMVDGEVNLTFVCFMYSKARSDLMLP---STSYTSFPIVLVVPSGGSISPMGRLT 336
            ..:.:| |...:.....:.:...|.: |..:...:|   ||.|....|:||.....:.|...:|:
  Fly   265 TFDESGRIFDEIFGHHADFSLGGFHF-KPSAGSEIPYSQSTYYFMSHIMLVTNLQSAYSAYEKLS 328

  Fly   337 RPFRYIIWSCILVSLIFGFVLI--CLLKITALPGLRNLVLGRRN----RLPFMGMWASLLGGLA- 394
            .||..::|..|      |.|||  |||       |..||..|.:    |.|:..:....:||..
  Fly   329 FPFTPLLWRAI------GLVLILACLL-------LMLLVRWRHHHELPRNPYYELLVLTMGGNLE 380

  Fly   395 -LYNPQRNFARYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVLAKDYEFRILPALR 458
             .:.|||..:|.:|:.||..||:||:.|...:|.||:....|:|.:::|||||:.:..::.....
  Fly   381 DRWVPQRFPSRLVLLTWLFATLVLRSGYQSGMYQLLRQDTQRNPPQTISEVLAQHFTIQLAEVNE 445

  Fly   459 TIFKDSMPTTNFHAVLSLE----ESLYRLRDEDDPGITVALLQPTVNQFDFRS-GPNKRHLTVLP 518
            .....|:|......::.||    :|...|..:......||:|.|......||. .|..|.|.::.
  Fly   446 ARILASLPELRPEQLVYLEGSELQSFPALAQQSGSSARVAILTPYEYFGYFRKVHPMSRRLHLVR 510

  Fly   519 DPLMTAPLTFYMRPHSYFKRRIDRLIMAMMSSGIVARYRKMYM-------DRIKRVSK------- 569
            :.:.|..|.||:|.||:....:::.|....:.|.:..:.:.|:       :.:.|::.
  Fly   511 ERIYTQQLAFYVRRHSHLVGVLNKQIQHAHTHGFLEHWTRQYVSAVDEKDESVARIASTSYSTLD 575

  Fly   570 --------------------RRNLEPKPLSIWRLSGIFVCCAGLYLVALIVFILEIL 606
                                |:|:    ||:..|:.:|.......|.|::||:||:|
  Fly   576 GIDGDPSLSESEEDQQVAPVRQNV----LSMRELAALFWLILWANLGAVVVFVLELL 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	20/62 (32%)
Ir7c	NP_001245572.1	Lig_chan	343..593	CDD:278489	71/296 (24%)
Ir7b	NP_572410.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463048
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25775
OrthoDB	1	1.010	-	-		D71073at33392
OrthoFinder	1	1.000	-	-		FOG0007621
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.960