DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir7c and Ir7a

DIOPT Version :9

Sequence 1:	NP_001245572.1	Gene:	Ir7c / 31692	FlyBaseID:	FBgn0029966	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_572406.1	Gene:	Ir7a / 31686	FlyBaseID:	FBgn0029961	Length:	614	Species:	Drosophila melanogaster

Alignment Length:	658	Identity:	134/658 - (20%)
Similarity:	244/658 - (37%)	Gaps:	156/658 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 TSTPLAVVQFPTSRESRRLHNDLIDAALGRSSGTGRIQFLLEDDRVEMTETDTDPPP---PSGLT 88
            :.:.|||:......|.|....:.:...:.||.|:            ||.......||   |:.
  Fly    45 SQSTLAVMDLTQDAEHRDERQEQLMTIILRSVGS------------EMALRTFQKPPAEVPAS-- 95

  Fly    89 GRPIAIWFLDSLRSYFRLEMYLNQLGSPYKRNGFFLVIYTGLEDQPMESLKIM---FRRLLNMYV 150
               ..::.::|.:::..|..:...:.|..:.|  ||::.|.......|.|:::   .|..:..:.
  Fly    96 ---FVVFLVNSAQAFNTLGFHFTDIHSTREFN--FLILLTHRMSSRAERLQVLRDISRTCVRFHT 155

  Fly   151 LNVNVFLQ-RDGTVHLYTYYPYGPHHCQSS-----LPVYYTAFQDLAAPANGFGLTKPLFPRKLT 209
            .||.:..: |||.|.:|.|.... ..|..|     :.:|..........|..|        .::.
  Fly   156 SNVILLTEKRDGVVLVYAYRLLN-MDCDLSVNLELIDIYKNGLFRHGHEARSF--------NRVL 211

  Fly   210 NMHGCEMVVATFEHRPYVIIEDDPKTPGGRS----IHGIEGLIFRSLAERMNFTIKLVEQKDKNR 270
            ::.||.:.|:.:...|:|....:...|..|:    :.||:|.:.:.||...:|.|.|.|..:|..
  Fly   212 SLSGCPLQVSWYPLPPFVSFIGNSSDPEERAQIWRLTGIDGELIKLLASIFDFRILLEEPCNKCL 276

  Fly   271 GEILPDGNFTGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLVVPSGGSISPMGRL 335
            ...:.| :.:|....::....::.......|.........::||....:|.::........:.:|
  Fly   277 SPDIKD-DCSGCFDQVIISNSSILIGAMSGSHQHRSHFSFTSSYHQSSLVFIMHMSSQFGAVAQL 340

  Fly   336 TRPFRYIIWSCILVSLIFGFVLICLLKITALPGLRNLVLGRRNRL---------PFMGMWASLLG 391
            ..||..|:|..::||.:                |..|||..||||         ..:.:..:|:|
  Fly   341 AVPFTVIVWLALVVSSL----------------LLVLVLWMRNRLVCGRSDLASHALQVLTTLMG 389

  Fly   392 G--LALYNPQRNFARYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKS-LSEVLAKDYEFRI 453
            .  .|...|:.:..|.:...|||..|:||..|.|:|:...: :....|:.: :||::..:|
  Fly   390 NPLEARSLPRSSRLRILYAGWLLLVLVLRVVYQGKLFDSFR-LPYHKPLPTEISELIRSNY---- 449

  Fly   454 LPALRTIFKDSMPTTNFHAVLSLEESLYRLRDEDDPGITVALLQPTVNQFDFRSGPNKR------ 512
                              .:::.|...|..|:     :||.....:.::||:..|..|.
  Fly   450 ------------------TLINQEYLDYYPRE-----LTVLTRNGSKDRFDYIQGLGKEGKFTTT 491

  Fly   513 -----------------HLTVLPDPLMTAPLTFYMRPHSYFKRRIDRLIMAMMSSGIV------- 553
                             .||.:.:.:....:..|:|.||..|...||.|..::|:||:
  Fly   492 SLIATMEYYNMMHWSTSRLTHIKEHIFLYQMVIYLRRHSLLKFAFDRKIKQLLSAGIIGYFVREF 556

  Fly   554 --ARYRKMYMDRIKRVSKRRNLEPKPLSIWRLSGIFVCCAGLYLVALI-------VFILEILTTN 609
              .:|||.:.:..:       :.|.||..:         .|||.::||       .||||:|:..
  Fly   557 DACQYRKPFEEDYE-------VTPIPLDSF---------CGLYYISLIWLSAAVVAFILELLSQR 605

  Fly   610 HRRLRRAF 617
            ...|||.|
  Fly   606 IVWLRRIF 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	16/65 (25%)
Ir7c	NP_001245572.1	Lig_chan	343..593	CDD:278489	57/293 (19%)
Ir7a	NP_572406.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25775
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007621
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920