Protein Alignment Ir7c and GRID2

DIOPT Version :10

• Sequence 1: NP_572411.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_011530195.2
• Gene: GRID2 / 2895
• HGNCID: 4576
• Length: 1035
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 68/303 - (22%)
• Similarity: 116/303 - (38%)
• Gaps: 57/303 - (18%)

  Fly   198 GLTKPLFPRKL-TNMHGCEMVVATFEHRPYVIIEDD----PKTPGGRSIHGIEGLIFRSLAERMN 257
            ||...|..:|| .||.|..:.|.|....|:|::.::    ||...|.||.     :..:|:..:.
Human   452 GLNGSLTDKKLENNMRGVVLRVVTVLEEPFVMVSENVLGKPKKYQGFSID-----VLDALSNYLG 511

  Fly   258 FTIKLVEQKDKNRGEILPDGNFTGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLV 322
            |..::....|...|....||.:.|::..:|....::.......:..|.:::..:|.|..:.:.::
Human   512 FNYEIYVAPDHKYGSPQEDGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVL 576

  Fly   323 VPSGGSISPMGRLTRPFRYIIWSCILVSLIFGFVLICLLKITALPGLRNLVLGRRNRLPFMGMWA 387
            :........|.....||...:|:||..:::...:|:.||.....|.|:            ||...
Human   577 LRRAEKTVDMFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNPPRLQ------------MGSMT 629

  Fly   388 SLLGGLALYN----------------PQRNFA-RYILVMWLLQTLILRAAYTGQLYLLLQDVEMR 435
            |    ..|||                |....| |.::..|.|..||:.::||..|...|....:.
Human   630 S----TTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTITRIE 690

  Fly   436 SPIKSLSEVLAKD-------------YEFRILPALRTIFKDSM 465
            |.|:||.: |:|.             ||...:..|....:|||
Human   691 SSIQSLQD-LSKQTEIPYGTVLDSAVYEHVRMKGLNPFERDSM 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_572411.1	Lig_chan-Glu_bd	225..287	CDD:214911	14/65 (22%)
		Lig_chan	343..592	CDD:459656	37/153 (24%)
GRID2	XP_011530195.2	Periplasmic_Binding_Protein_type1	92..457	CDD:471960	2/4 (50%)
		PBP2_iGluR_delta_2	468..834	CDD:270449	61/287 (21%)