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Protein Alignment Ir7c and GRIA3

DIOPT Version :9

Sequence 1:	NP_001245572.1	Gene:	Ir7c / 31692	FlyBaseID:	FBgn0029966	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_000819.4	Gene:	GRIA3 / 2892	HGNCID:	4573	Length:	894	Species:	Homo sapiens

Alignment Length:	498	Identity:	97/498 - (19%)
Similarity:	180/498 - (36%)	Gaps:	130/498 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   216 MVVATFEHRPYVIIEDDPKTPGGRSIHGIEGL---IFRSLAERMNFTIKLVEQKDKNRGEILPDG 277
            :||.|....|||:.:.:.:...|...:  ||.   :...:|:.:....||         .|:.||
Human   425 IVVTTILESPYVMYKKNHEQLEGNERY--EGYCVDLAYEIAKHVRIKYKL---------SIVGDG 478

  Fly   278 NF----------TGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLVVPSGGSISP- 331
            .:          .|::..:|.|..::.......:..|.:::..|..:.|..|.:::.......|
Human   479 KYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 543

  Fly   332 MGRLTRPFRYIIWSCILVSLIFGFVLICLLKITALPGLRNLVLGRRNRLP--------------- 381
            :.....|..|.||.||:.:.| |..::..|.....|  ....|...|..|
Human   544 VFSFLDPLAYEIWMCIVFAYI-GVSVVLFLVSRFSP--YEWHLEDNNEEPRDPQSPPDPPNEFGI 605

  Fly   382 FMGMWASLLGGLAL-----YNPQRNFARYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSL 441
            |..:|.||  |..:     .:|:....|.:..:|...|||:.::||..|...|....|.|||:|
Human   606 FNSLWFSL--GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES- 667

  Fly   442 SEVLAKDYEFRILPALRTIFKDSMPTTNF--HAVLSLEESLYRLRDEDDPGI---TVA------- 494
            :|.|||..|.    |..|:  ||..|..|  .:.:::.|.::......:|.:   |.|
Human   668 AEDLAKQTEI----AYGTL--DSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVR 726

  Fly   495 --------LLQPTVNQFDFRSGP-----------NKRHLTVLPDPLMTAPLTFYMRPHSYFKRRI 540
                    ||:.|:|::..:..|           :|.:....|             ..|..:..:
Human   727 KSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATP-------------KGSALRNAV 778

  Fly   541 DRLIMAMMSSGIVARYR-KMYMDRIKRVSKRRNLEPK--PLSIWRLSGIFVCCAGLYLVALIVFI 602
            :..::.:...|::.:.: |.:.|:.:..|...:.:.|  .||:..::|:|....|...:|::|.:
Human   779 NLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVAL 843

  Fly   603 LEIL--------------------------TTNHRRLRRAFNV 619
            :|..                          |.|:...|..:||
Human   844 IEFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNV 886

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.