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Protein Alignment Ir7c and Grin2a

DIOPT Version :9

Sequence 1:	NP_001245572.1	Gene:	Ir7c / 31692	FlyBaseID:	FBgn0029966	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_036705.3	Gene:	Grin2a / 24409	RGDID:	2737	Length:	1464	Species:	Rattus norvegicus

Alignment Length:	711	Identity:	145/711 - (20%)
Similarity:	263/711 - (36%)	Gaps:	169/711 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 WAIDNYYGMATSTPLAVVQFPTSRESRRLHNDLIDAALGRSSGTGRIQFLLEDDRV-EMTETDTD 80
            |.:.|...:.||...|..|.    :.:::|:.:|            :.:..:|:.| .::|..:
  Rat   198 WDMQNVITLDTSFEDAKTQV----QLKKIHSSVI------------LLYCSKDEAVLILSEARS- 245

  Fly    81 PPPPSGLTGRPIAIWFLDSLRSYFRLEMYLNQLGSPYKRNGFFLVIYTGLEDQPMESLKIMFRRL 145
                .||||... .|.:.||.| ...|:...:..|     |...|.|    |....||:...|..
  Rat   246 ----LGLTGYDF-FWIVPSLVS-GNTELIPKEFPS-----GLISVSY----DDWDYSLEARVRDG 295

  Fly   146 LNMYVLNVNVFLQRDGTVHLYTYYP------YG-------PHHCQSSLPVYYT-AFQDLAAPANG 196
            |.:.....:..|::      ::|.|      ||       |.|......|..| ..:||:....|
  Rat   296 LGILTTAASSMLEK------FSYIPEAKASCYGQAEKPETPLHTLHQFMVNVTWDGKDLSFTEEG 354

  Fly   197 F----------------------------GLTKPLFPRKLTNMHGCE-----MVVATFEHRPYVI 228
            :                            .|...::|| ..:...||     :.:.|.|..|:||
  Rat   355 YQVHPRLVVIVLNKDREWEKVGKWENQTLSLRHAVWPR-YKSFSDCEPDDNHLSIVTLEEAPFVI 418

  Fly   229 IED-DPKT--------PGGRSI----HGIEGL------------IFRSLAERMNFTIKLVEQKDK 268
            :|| ||.|        |..:.:    ...||:            |.:.|:..:.||..|....:.
  Rat   419 VEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNG 483

  Fly   269 NRGEILPDGNFTGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPI-VLVVPSGGSISPM 332
            ..|:.: :..:.|::..:|.....:.......::.||:::..|..:....| |:|..|.|::||.
  Rat   484 KHGKKV-NNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPS 547

  Fly   333 GRLTRPFRYIIWSCILVS-LIFGFVLICLLKITALPGL-RNLVLGRRNRLPFM----GMWASLLG 391
            ..| .||...:|..:.|. ||...:.:.:.:..:..|. |||..|:....|..    .:|  ||.
  Rat   548 AFL-EPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIW--LLW 609

  Fly   392 GLA------LYNPQRNFARYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVLAKDYE 450
            ||.      :.||:...::.::.:|....:|..|:||..|...:...|....:..||     |.:
  Rat   610 GLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLS-----DKK 669

  Fly   451 FRILPALRTIFKDSMPTTNFHAVL--SLEESL---------YRLRDEDDPGITVALLQPTVNQFD 504
            |: .|      .|..|...|..|.  |.|.::         |..| .:..|:..||:.....:.|
  Rat   670 FQ-RP------HDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTR-FNQRGVEDALVSLKTGKLD 726

  Fly   505 ----------FRSGPNK--RHLTVLPDPLM-TAPLTFYMRPHSYFKRRIDRLIMAMMSSGIVARY 556
                      :::|.::  :.:|:....:. |......::..|.:||:||..::..:..|.:...
  Rat   727 AFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEEL 791

  Fly   557 RKMYMDRIKRVSKRRNLEPKPLSIWRLSGIFVCCAGLYLVALIVFILEILTTNHRRLRRAF 617
            ..:::..|.. :::..:....|.|..::|:|...|....::||.||.|.|.  :.:||..|
  Rat   792 ETLWLTGICH-NEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLF--YWKLRFCF 849

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.