Protein Alignment Ir7c and glr-6

DIOPT Version :9

• Sequence 1: NP_001245572.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_741822.2
• Gene: glr-6 / 180955
• WormBaseID: WBGene00001617
• Length: 844
• Species: Caenorhabditis elegans
• Alignment Length: 622
• Identity: 120/622 - (19%)
• Similarity: 210/622 - (33%)
• Gaps: 207/622 - (33%)

  Fly    83 PPSGLTGR------------PIAIWFLDSLRSYFRLEMYLNQLGSPYKRNGFFLVIYTGLEDQPM 135
            |..||||:            .:.||           ||.:...|           ::||:.....
 Worm   339 PFKGLTGKISFNGTSDRSDSELHIW-----------EMGITGAG-----------LHTGIWKSTW 381

  Fly   136 ESLKIMFRRLLNMYVLNVNVFLQRDGTVHLYTYYPYGPH-HCQSSLPVYYTAFQDLAAPANGFGL 199
            |..|     .|.|...|:.                 |.| |.|:|:....|.
 Worm   382 EGSK-----ELTMLAKNIP-----------------GTHEHYQASVRESRTL------------- 411

  Fly   200 TKPLFPRKLTNMHGCEMVVATFEHRPYVIIEDDPKTPGGRSIHGIEGL---IFRSLAERM--NFT 259
                   |:|::|          .:||||   :...|.||..|  ||.   :...|||.:  |:|
 Worm   412 -------KVTSIH----------EKPYVI---EKIMPDGRIKH--EGFCVDLLDKLAEMLHFNYT 454

  Fly   260 IKLVEQKDKNRGEILPDG--NFTGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLV 322
            :|:|  ||...|| ..:|  .:.|::..::.|:.::.......:..|.:::..:..:....|.::
 Worm   455 LKIV--KDNKYGE-RKNGTDEWDGMIGEILRGDADMAVAPITVTATRLEVIDFTDPFLQLGISML 516

  Fly   323 V--PSGGSISPMGRLTRPFRYIIWSCILVSLIFGFVLICLLKI------TALPGLRNLVLGRRNR 379
            :  |:..|.|.:.|...|....:|:...::.:...:|:.:..:      ||...::|.|
 Worm   517 MRQPNPKSSSSLTRFLWPLSASVWTFSAIATVITALLVTVAAVLSPKESTAEFKIQNSV------ 575

  Fly   380 LPFMGMW---ASLLGGLALYNPQRNFARYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSL 441
                  |   ..||...:.||.|....|.|..:|...||:|.|.||.....||.......|..|.
 Worm   576 ------WYLVCILLRAGSGYNCQAGATRLISAVWWSFTLVLIAQYTANFAALLTVDRKSMPFNSF 634

  Fly   442 SEVLAKDYEFRILPALRTIFKDSMPTTNFHAVL----------SLEESLYRL---RDEDDPGITV 493
            .| |....|:                 ||.::|          |..|:..||   ....:|...|
 Worm   635 EE-LGNQTEY-----------------NFGSILGGSTMQFFKYSRIETFRRLWERMQSAEPSAFV 681

  Fly   494 ALLQPTVNQFDFRSGPNKRHLTVLPDPLMTAPLT-------------------FYMRPHSYFKRR 539
            ......||:.     .|::::.::....:...:|                   ..:...|.::.:
 Worm   682 GTNHEGVNRV-----LNEKYVFLMESATLDYQVTQNCNLTRVGNVVLGSNGYSIALPKGSKWREK 741

  Fly   540 IDRLIMAMMSSGIVARYRKMYMDRIKRVSKRRNLEPKPL-------SIWRL-------SGIFVCC 590
            :.|.|:.:...||:...:..:..  |...:.::.||:.|       :::.|       |||.|.|
 Worm   742 LTRQILDLNEKGIILMLKNNWWK--KSQQECQSSEPEDLQTALGAENVYGLFLLLALGSGIGVLC 804

  Fly   591 AGLYLVALIVF-----------ILEILTTNHRRLRRA 616
            |.|.....|.|           :.:::.|.|..:|.:
 Worm   805 AVLEHTHFIFFEKNKRNGQTPKLQQMIETIHAEIRNS 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	23/68 (34%)
		Lig_chan	343..593	CDD:278489	57/304 (19%)
glr-6	NP_741822.2	PBP1_iGluR_non_NMDA-like	21..394	CDD:380591	16/81 (20%)
		PBP2_iGluR_Kainate	409..764	CDD:270432	81/427 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910